A patient is ordered vancomycin 1g IV over 60 minutes. After 10 minutes, the patient develops flushing and erythema on the neck and face. What is the most likely cause?
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A
Allergic reaction requiring epinephrine
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B
Red Man Syndrome due to rapid infusion rate
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C
Extravasation of vancomycin
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D
Anaphylaxis requiring immediate discontinuation