HRT HRT for Menopause & Perimenopause 2

Question 1

The WHI study findings regarding combined HRT were MOST applicable to which patient population?

Accepted Answer

Older postmenopausal women (average age 63) with pre-existing cardiovascular risk

Answer

The WHI study enrolled women with an average age of 63 years, many with pre-existing cardiovascular risk factors, limiting applicability to younger, newly menopausal women.

Question 2

The 'timing hypothesis' of HRT suggests that cardiovascular benefits are most likely when HRT is initiated within how many years of menopause onset?

Accepted Answer

Within 10 years or before age 60

Answer

The timing hypothesis holds that initiating HRT within 10 years of menopause or before age 60 preserves cardiovascular benefit, while later initiation may increase risk.

Question 3

Which progesterone/progestogen is considered to have the most favorable safety profile regarding breast cancer risk in HRT?

Accepted Answer

Micronized progesterone (Prometrium)

Answer

Micronized progesterone has less proliferative effect on breast tissue compared to synthetic progestins like MPA, and observational studies suggest a more favorable breast cancer profile.

Question 4

Which symptom cluster is associated with the genitourinary syndrome of menopause (GSM)?

Accepted Answer

Vaginal dryness, dyspareunia, and urinary urgency

Answer

GSM encompasses vulvovaginal atrophy and urinary tract changes including dryness, painful intercourse, and urgency due to estrogen loss in genital and lower urinary tract tissues.

Question 5

A perimenopausal woman reports irregular cycles, hot flashes, and low libido with normal FSH levels. What explains the normal FSH?

Accepted Answer

FSH fluctuates during perimenopause and a single reading may not reflect overall status

Answer

Perimenopause is characterized by erratic hormonal fluctuation; FSH may be normal or even low on the day of testing despite overall declining ovarian reserve.

HRT - Hormone Replacement Therapy Certification Practice Test

HRT - Hormone Replacement Therapy Certification Practice Test

HRT HRT for Menopause & Perimenopause 2