HRT HRT Delivery Methods & Administration

Question 1

Which HRT delivery method provides the most consistent serum hormone levels by bypassing first-pass hepatic metabolism?

Accepted Answer

Transdermal patch

Answer

Oral tablet

Answer

Vaginal cream

Answer

Sublingual drop

Question 2

What is the primary advantage of subcutaneous pellet implants over other HRT delivery methods?

Accepted Answer

Sustained hormone release over 3–6 months

Answer

Immediate dose adjustment flexibility

Answer

Lowest cost option

Answer

Easiest self-administration

Question 3

When applying a transdermal estrogen gel, which site is MOST appropriate?

Accepted Answer

Upper arm or inner thigh

Answer

Scalp

Answer

Face

Answer

Breast tissue

Question 4

Which route of progesterone administration is associated with the lowest risk of hepatic side effects?

Accepted Answer

Vaginal suppository

Answer

Oral tablet

Answer

Intramuscular injection

Answer

Sublingual tablet

Question 5

Intramuscular testosterone cypionate injections are typically administered at what interval for male HRT?

Accepted Answer

Every 1–2 weeks

Answer

Daily

Answer

Monthly

Answer

Every 6 months

Question 6

Which HRT formulation is considered a bioidentical hormone because its molecular structure is identical to endogenous human estradiol?

Accepted Answer

17β-estradiol

Answer

Conjugated equine estrogen

Answer

Ethinyl estradiol

Answer

Mestranol