HRT Study Guide 2026
Everything you need to pass the HRT exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
📋 HRT Exam Format at a Glance
📚 HRT Topics to Study (22)
✍️ Sample HRT Questions & Answers
1. When monitoring a male patient on TRT, how frequently should PSA and hematocrit be checked after the first year of stable therapy?
After the initial more frequent monitoring period, stable TRT patients should have PSA and hematocrit checked at least annually to detect prostate or erythrocytosis changes.
2. Which cardiovascular risk factor, if present in a woman under 60, does NOT necessarily preclude low-dose transdermal HRT for menopausal symptoms?
Well-controlled hypertension without end-organ damage in a woman under 60 is generally considered a relative, not absolute, contraindication when using transdermal HRT.
3. Non-hormonal pharmacologic options for menopausal hot flashes include which of the following?
Low-dose SSRIs (paroxetine, escitalopram), SNRIs (venlafaxine), and gabapentin are evidence-based non-hormonal options for reducing menopausal vasomotor symptoms.
4. What is the primary advantage most often cited for compounded bioidentical HRT over standard commercial preparations?
The principal advantage of compounded BHRT is the ability to customize hormone doses, combinations, and delivery forms to meet each patient's specific requirements.
5. Which lipid parameter may worsen with injectable testosterone therapy compared to baseline?
Injectable testosterone therapy, particularly at higher doses, can decrease HDL cholesterol ('good' cholesterol), which is an important cardiovascular risk marker to monitor.
6. Which documentation practice protects a practitioner from liability when a patient with a relative contraindication to HRT chooses to proceed after counseling?
Thorough shared decision-making documentation demonstrates that the patient was fully informed, understood the risks, and voluntarily chose to proceed, establishing the legal basis for proceeding with caution.