HRT HRT Delivery Methods & Administration 2

Question 1

A patient on oral estrogen therapy develops elevated triglycerides. What delivery method change should be considered?

Accepted Answer

Switch to transdermal estrogen

Answer

Increase oral estrogen dose

Answer

Add a statin and continue orals

Answer

Switch to intramuscular progesterone

Question 2

What is the recommended rotation practice for transdermal estrogen patches to minimize skin irritation?

Accepted Answer

Rotate sites with each patch change

Answer

Always apply to the same site

Answer

Apply only to the abdomen

Answer

Change site monthly

Question 3

Testosterone pellet insertion is performed in which anatomical location?

Accepted Answer

Upper buttock or hip subcutaneous tissue

Answer

Intra-abdominal cavity

Answer

Deltoid muscle

Answer

Antecubital fossa

Question 4

Which vehicle base is used in most compounded transdermal hormone creams to enhance skin penetration?

Accepted Answer

PLO (Pluronic Lecithin Organogel)

Answer

Petroleum jelly

Answer

Aqueous saline solution

Answer

Isopropyl alcohol alone

Question 5

For a patient who cannot tolerate oral progesterone due to sedation, which alternative route minimizes CNS side effects?

Accepted Answer

Vaginal progesterone

Answer

Intranasal progesterone

Answer

Higher-dose oral progesterone

Answer

Intramuscular estrogen

Question 6

When calculating testosterone pellet dosing, which factor is the PRIMARY determinant of pellet quantity?

Accepted Answer

Patient's body weight and activity level

Answer

Patient's age alone

Answer

Physician preference only

Answer

Insurance formulary limits