GPhC Patient Safety

Question 1

A pharmacist identifies that a patient has been prescribed methotrexate 10mg daily instead of 10mg weekly. What is the most critical immediate action?

Accepted Answer

Contact the prescriber immediately to clarify the dosing frequency before dispensing

Answer

Daily methotrexate dosing (instead of weekly) is a well-known fatal prescribing error that has caused multiple patient deaths. The pharmacist must contact the prescriber immediately to clarify and correct the prescription. This is a never-event in the NHS. Dispensing as written, even with verbal advice, is not acceptable.

Question 2

The Yellow Card Scheme is used to report suspected adverse drug reactions (ADRs) to which UK organisation?

Accepted Answer

Medicines and Healthcare products Regulatory Agency (MHRA)

Answer

The Yellow Card Scheme is operated by the MHRA and is the UK system for collecting information on suspected adverse drug reactions. Healthcare professionals and patients can report via yellow cards, online, or through the Yellow Card app. It is vital for post-marketing surveillance.

Question 3

A patient collecting a dispensed prescription notices that the tablets look different from their usual supply. What should the pharmacist do?

Accepted Answer

Check the dispensed item against the prescription, confirm it is correct, and explain any changes such as a different generic brand

Answer

Patients often receive different generic brands due to supply chain changes. The pharmacist should verify the dispensed item is correct, then clearly explain to the patient why the appearance has changed whilst confirming it contains the same active ingredient at the same dose. This builds trust and reduces non-adherence.

Question 4

Which of the following is an example of a high-risk medicine that requires additional safety checks in community pharmacy, as identified by NHS patient safety alerts?

Accepted Answer

Warfarin tablets

Answer

Warfarin is classified as a high-risk medicine due to its narrow therapeutic index, need for INR monitoring, significant drug and food interactions, and potential for serious bleeding. NHS patient safety alerts require additional checks for high-risk medicines including anticoagulants, insulin, opioids, and methotrexate.

Question 5

A dispensing error has occurred in the pharmacy. According to best practice, what should the pharmacy do after ensuring patient safety?

Accepted Answer

Conduct a root cause analysis and report the error through the local incident reporting system

Answer

A just culture approach requires root cause analysis to identify system failures rather than blaming individuals. All errors should be reported through the incident reporting system (such as NRLS/LFPSE) regardless of whether harm occurred, as near-misses provide valuable learning opportunities for preventing future errors.

GPhC Registration Practice Test

GPhC Registration Practice Test

GPhC Patient Safety