GPHC Study Guide 2026
Everything you need to pass the GPHC exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
📋 GPHC Exam Format at a Glance
📚 GPHC Topics to Study (50)
✍️ Sample GPHC Questions & Answers
1. Which drug is used as prophylaxis against Pneumocystis jirovecii pneumonia (PCP) in immunosuppressed patients?
Co-trimoxazole is first-line PCP prophylaxis in HIV patients with CD4 <200 cells/µL and other immunosuppressed patients (e.g., on high-dose corticosteroids, post-transplant).
2. When dispensing a prescription for a Schedule 2 controlled drug, what specific record must be made in the controlled drug register?
The Misuse of Drugs Regulations 2001 require comprehensive entries in the CD register for Schedule 2 drugs including: date of supply, drug name/form/strength, quantity supplied, person collecting, prescriber name and address, and (good practice) a running balance. Entries must be made on the day of supply or the next day.
3. A pharmacist needs to prepare 200mL of a 5% w/v solution from a 20% w/v stock solution and water. What volumes of stock solution and water are needed?
Using C₁V₁ = C₂V₂: 20% × V₁ = 5% × 200mL. V₁ = (5 × 200) ÷ 20 = 50mL of stock solution. Water needed = 200mL - 50mL = 150mL.
4. What is the osmolarity of normal saline (0.9% NaCl) approximately?
0.9% NaCl dissociates into Na+ and Cl−, each at 154 mmol/L, giving approximately 308 mOsm/L, which is isotonic with blood.
5. What is meant by 'medication reconciliation' at hospital discharge?
Discharge medicines reconciliation ensures intentional medication changes (stopped, started, dose changes) are documented, communicated to GP, and explained to the patient to prevent post-discharge errors.
6. Which of the following is NOT permitted on a Schedule 2 CD prescription?
CD prescriptions must state the total quantity in both words AND figures (e.g., thirty (30) tablets). Words alone are not sufficient; both are legally required.
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- A timed, full-length GPhC mock exam — 160 questions in 270 minutes with a 70% pass mark, modeled on the official exam's question count and time limit, followed by a score report broken down by exam domain.
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How this page was made: written with AI tools and published by Nathan Beja, founder of Practice Test Geeks, who is responsible for its content. Exam facts are checked against the official sources listed below. Not reviewed by a subject-matter expert. Editorial policy
Sources & references
Exam facts on this page (fees, format, dates, passing scores) are checked against these official sources; the date is our last check. Editorial policy
- pharmacyregulation.org — Eligibility, exam dates, fees, registration deadline, score release, exam information · verified Oct 2026
- psni.org.uk — Retake policy · verified Oct 2026
- assets.pharmacyregulation.org — Test delivery, exam format, passing score, time limit · verified Oct 2026