GPhC Pharmaceutical Sciences & Calculations

Question 1

A patient requires 250 mg of amoxicillin. The suspension available is 125 mg/5 mL. What volume should be dispensed?

Accepted Answer

10 mL

Answer

5 mL

Answer

2.5 mL

Answer

15 mL

Question 2

What is the percentage concentration (w/v) of a solution containing 2 g of drug in 250 mL?

Accepted Answer

0.8% w/v

Answer

2% w/v

Answer

0.4% w/v

Answer

1% w/v

Question 3

A prescription requires 0.5% w/v hydrocortisone cream in 50 g. How many milligrams of hydrocortisone are needed?

Accepted Answer

250 mg

Answer

500 mg

Answer

50 mg

Answer

100 mg

Question 4

Which route of administration avoids first-pass metabolism most effectively?

Accepted Answer

Intravenous

Answer

Oral

Answer

Sublingual

Answer

Rectal

Question 5

What does a drug's half-life determine?

Accepted Answer

Time to reach steady state

Answer

Peak plasma concentration

Answer

Volume of distribution

Answer

Bioavailability

Question 6

Which formulation type is designed to release drug over an extended period to reduce dosing frequency?

Accepted Answer

Modified-release tablet

Answer

Effervescent tablet

Answer

Dispersible tablet

Answer

Enteric-coated tablet