FPGEE Trivia FPGEE Exam

Question 1

Which organization administers the FPGEE in the United States?

Accepted Answer

NABP

Answer

The National Association of Boards of Pharmacy (NABP) administers the FPGEE.

Question 2

What is the primary mechanism of action of metformin in treating type 2 diabetes?

Accepted Answer

Decreases hepatic glucose production

Answer

Metformin primarily works by inhibiting hepatic gluconeogenesis, reducing liver glucose output.

Question 3

Which cytochrome P450 enzyme is responsible for metabolizing approximately 50% of all marketed drugs?

Accepted Answer

CYP3A4

Answer

CYP3A4 is the most abundant hepatic CYP enzyme and metabolizes roughly half of all drugs.

Question 4

A patient taking warfarin begins a course of fluconazole. What is the expected effect?

Accepted Answer

Increased anticoagulation

Answer

Fluconazole inhibits CYP2C9, reducing warfarin metabolism and increasing anticoagulant effect.

Question 5

What is the controlled substance schedule for hydrocodone combination products in the US?

Accepted Answer

Schedule II

Answer

Since 2014, all hydrocodone combination products were rescheduled to Schedule II by the DEA.

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