Free FPGEE Exam Question and Answers โ Questions and Answers
Question 1: Drotrecogin alfa is marketed in which of the following forms? <br> I. Oral suspension; 200 mg/5 mL and 400mg/5 mL <br> II. Lyophilized powder for injection; 5 and 20 mg <br> III. Tablet; 200, 250, and 500 mg <br> IV. Capsule; 250 and 500 mg
- I, II, and III only
- II only (Correct answer)
- I and IV only
- All of the above
Correct answer: II only
Drotrecogin alfa (Xigris) was an anticoagulant medication specifically formulated for intravenous administration. It was marketed as a lyophilized powder for injection, available in 5 mg and 20 mg vials, which aligns with option II. It was never available in oral suspension, tablet, or capsule forms, as its therapeutic action required direct intravenous delivery. (Note: Drotrecogin alfa was voluntarily withdrawn from the market in 2011.)
Question 2: Which of the following blood results would be accurate in a case of anemia caused by iron deficiency?
- Increased MCV and an increased RDW
- Decreased MCV and an increased MCHC
- Decreased MCV and an decreased RDW
- Decreased MCV and an increased RDW (Correct answer)
Correct answer: Decreased MCV and an increased RDW
Iron deficiency anemia typically presents as a microcytic, hypochromic anemia, meaning the red blood cells are smaller than normal, resulting in a decreased Mean Corpuscular Volume (MCV). An increased Red Cell Distribution Width (RDW) indicates a greater variation in the size of red blood cells (anisocytosis), which is a characteristic finding in iron deficiency anemia as the body attempts to produce new, often smaller, red blood cells.
Question 3: Which of the following is an agonist with opioid properties?
- Pemoline
- Diltiazem
- Phenobarbital
- Propoxyphene (Correct answer)
Correct answer: Propoxyphene
Propoxyphene is classified as an opioid analgesic, meaning it acts as an agonist at opioid receptors in the central nervous system to produce pain relief. It is structurally related to methadone and exerts its therapeutic effects by binding to mu-opioid receptors. The other listed options, Pemoline, Diltiazem, and Phenobarbital, belong to different drug classes and do not possess opioid properties.
Question 4: Which of the following metals explodes when it comes into contact with water?
- Silver
- Chromium
- Manganese
- Sodium (Correct answer)
Correct answer: Sodium
Sodium is an alkali metal, known for its extreme reactivity with water. When it comes into contact with water, a vigorous exothermic reaction occurs, producing hydrogen gas and sodium hydroxide. The heat generated by this reaction is often sufficient to ignite the hydrogen gas, leading to a rapid combustion or explosion.
Question 5: Which of the following elements exhibits delocalized "sea of electrons" bonding?
- Sulfur
- Copper (Correct answer)
- Nitrogen
- Fluorine
Correct answer: Copper
Copper is a metal, and metals are characterized by metallic bonding, which involves a 'sea of electrons.' In this bonding model, valence electrons are delocalized and shared among all the positively charged metal ions. This delocalized electron cloud allows for the high electrical and thermal conductivity typical of metals.
Question 6: GERD, moderate hypertension, hyperthyroidism, hypercholesterolemia, and Type II diabetes with a 5-year history have all been identified in a 56-year-old female patient. Metformin, Glyburide, Propylthiouracil, Lansoprazole, Atorvastatin, and Hydrochlorothiazide are some of the medications. A1c is 9.8%, TSH is 2.7, Hgb is 12.2 and total cholesterol is 130mg/dL according to recent lab results. A physical examination indicates a resting heart rate of 98 and a blood pressure reading of 128/76. The patient reports having thirst, weariness, and cramping. Which drug on the list below might require modification?
- Propylthiouracil
- Atorvastatin
- Metformin, glyburide, and atorvastatin (Correct answer)
- Metformin and glyburide
Correct answer: Metformin, glyburide, and atorvastatin
The patient's A1c of 9.8% indicates uncontrolled Type II diabetes, suggesting that the current dosages of metformin and glyburide are insufficient and require modification to improve glycemic control. Additionally, the reported muscle cramps and fatigue are common side effects of statins like atorvastatin, indicating that this medication might also need adjustment or a different statin considered to alleviate these symptoms. The thyroid and cholesterol levels are within acceptable ranges, making those medications less of a priority for immediate modification based on the presented issues.
Question 7: The patient is displaying symptoms of uncontrolled diabetes (an rise in A1c) as well as a negative side effect from taking statins (muscle cramps, fatigue). The results of thyroid tests are normal. The dosages of the statins and hypoglycemics should be changed.
- Viruses are not composed of cells.
- Viruses can infect all types of living organisms.
- Viruses can only reproduce using a cellโs machinery.
- All of the above (Correct answer)
Correct answer: All of the above
Viruses are unique biological entities that are not composed of cells; instead, they consist of genetic material (DNA or RNA) encased in a protein coat. They are obligate intracellular parasites, meaning they can only reproduce by infecting a host cell and utilizing its cellular machinery. Viruses are highly diverse and capable of infecting all types of living organisms, from bacteria to plants and animals.
Drotrecogin alfa is marketed in which of the following forms?
I.
Oral suspension; 200 mg/5 mL and 400mg/5 mL
II.
Lyophilized powder for injection; 5 and 20 mg
III.
Tablet; 200, 250, and 500 mg
IV.
Capsule; 250 and 500 mg