A patient is transported after ingesting methanol. Metabolic acidosis with a high anion gap and elevated osmol gap is present. What is the mechanism of methanol toxicity?
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A
Direct hepatocellular necrosis from methanol itself
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B
Conversion to formaldehyde and formic acid by alcohol dehydrogenase
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C
Competitive inhibition of cytochrome P450 enzymes
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D
Direct renal tubular toxicity from the parent compound