CFRN Study Guide 2026
Everything you need to pass the CFRN exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
📋 CFRN Exam Format at a Glance
📚 CFRN Topics to Study (69)
✍️ Sample CFRN Questions & Answers
1. Which pupillary finding is most consistent with uncal herniation in a TBI patient?
Uncal herniation compresses CN III on the ipsilateral side, causing a fixed, dilated pupil on the same side as the expanding lesion.
2. During flight transport of a postpartum patient with uterine atony unresponsive to oxytocin, which second-line uterotonic is CONTRAINDICATED in a patient with asthma?
Carboprost (15-methyl PGF2α) is contraindicated in patients with asthma because it can cause severe bronchospasm.
3. A patient presents with mydriasis, dry flushing skin, urinary retention, tachycardia, and delirium after ingesting an unknown substance. Which toxidrome is present?
The classic anticholinergic toxidrome ('mad as a hatter, red as a beet, dry as a bone, blind as a bat, hot as Hades') includes mydriasis, hyperthermia, dry skin, urinary retention, and delirium.
4. Henry's Law is most clinically relevant for the flight nurse when managing a patient with:
Henry's Law states that the amount of gas dissolved in liquid is proportional to its partial pressure; decompression sickness results from nitrogen bubbling out of solution as pressure decreases.
5. Serum lactate levels are used in shock assessment primarily because elevated lactate indicates:
Elevated lactate reflects anaerobic metabolism occurring when tissues are underperfused, making it a key marker of shock severity and resuscitation adequacy.
6. Charles' Law describes the relationship between gas temperature and volume. This law is most relevant during aeromedical transport when:
Charles' Law (volume varies directly with temperature at constant pressure) is relevant for air splints, which may contract in cold temperatures and require reassessment.