CCTC Organ-Specific Transplant Knowledge 2

Question 1

Which hemodynamic parameter is most critical to optimize in a potential heart donor to ensure graft viability?

Accepted Answer

Mean arterial pressure ≥60 mmHg

Answer

Maintaining mean arterial pressure ≥60 mmHg ensures adequate coronary perfusion and preserves heart graft function.

Question 2

What is the maximum recommended cold ischemia time for a transplanted kidney to minimize delayed graft function?

Accepted Answer

24 hours

Answer

Kidney cold ischemia time should ideally be kept under 24 hours to reduce the risk of delayed graft function.

Question 3

In liver transplantation, which condition in the recipient is associated with the highest urgency on the UNOS waiting list?

Accepted Answer

Acute liver failure with life expectancy <7 days (Status 1A)

Answer

Status 1A designates patients with acute liver failure and predicted survival less than 7 days without transplant, conferring highest priority.

Question 4

Which lung function parameter is the primary determinant when evaluating a potential lung donor for suitability?

Accepted Answer

PaO2/FiO2 ratio (P/F ratio) ≥300

Answer

A P/F ratio ≥300 on 100% FiO2 and 5 cmH2O PEEP indicates adequate gas exchange and donor lung viability.

Question 5

Following pancreas transplantation, which laboratory value is the most direct indicator of graft exocrine function failure?

Accepted Answer

Urine amylase (in bladder-drained grafts)

Answer

In bladder-drained pancreas transplants, a fall in urine amylase is the earliest and most sensitive marker of exocrine graft rejection.

CCTC - Certified Clinical Transplant Coordinator Practice Test