CCTC Organ-Specific Transplant Knowledge 2

Question 1

Which hemodynamic parameter is most critical to optimize in a potential heart donor to ensure graft viability?

Accepted Answer

Mean arterial pressure ≥60 mmHg

Answer

Central venous pressure 8-12 mmHg

Answer

Pulmonary capillary wedge pressure >18 mmHg

Answer

Heart rate >100 bpm

Question 2

What is the maximum recommended cold ischemia time for a transplanted kidney to minimize delayed graft function?

Accepted Answer

24 hours

Answer

12 hours

Answer

18 hours

Answer

36 hours

Question 3

In liver transplantation, which condition in the recipient is associated with the highest urgency on the UNOS waiting list?

Accepted Answer

Acute liver failure with life expectancy <7 days (Status 1A)

Answer

Hepatitis C cirrhosis with MELD 25

Answer

Alcoholic hepatitis with MELD 30

Answer

Hepatocellular carcinoma within Milan criteria

Question 4

Which lung function parameter is the primary determinant when evaluating a potential lung donor for suitability?

Accepted Answer

PaO2/FiO2 ratio (P/F ratio) ≥300

Answer

FEV1/FVC ratio

Answer

Residual volume

Answer

Diffusing capacity (DLCO)

Question 5

Following pancreas transplantation, which laboratory value is the most direct indicator of graft exocrine function failure?

Accepted Answer

Urine amylase (in bladder-drained grafts)

Answer

Serum amylase

Answer

Serum lipase

Answer

Blood glucose

Question 6

A heart transplant candidate has a panel reactive antibody (PRA) of 85%. What is the primary clinical implication?

Accepted Answer

High likelihood of hyperacute rejection without prospective crossmatch

Answer

Reduced risk of acute rejection

Answer

Requirement for ABO-incompatible transplant protocol

Answer

Automatic removal from the waiting list

Question 7

Which preservation solution is most commonly used for kidney and liver procurement during multi-organ procurement?

Accepted Answer

University of Wisconsin (UW) solution

Answer

Normal saline

Answer

Lactated Ringer's solution

Answer

Euro-Collins solution