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Organ-Specific Transplant Knowledge Flashcards

7 cards from real CCTC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Organ-Specific Transplant Knowledge flashcards as text

  1. Which hemodynamic parameter is most critical to optimize in a potential heart donor to ensure graft viability?

    Answer: Mean arterial pressure ≥60 mmHg

    Maintaining mean arterial pressure ≥60 mmHg ensures adequate coronary perfusion and preserves heart graft function.

  2. What is the maximum recommended cold ischemia time for a transplanted kidney to minimize delayed graft function?

    Answer: 24 hours

    Kidney cold ischemia time should ideally be kept under 24 hours to reduce the risk of delayed graft function.

  3. In liver transplantation, which condition in the recipient is associated with the highest urgency on the UNOS waiting list?

    Answer: Acute liver failure with life expectancy <7 days (Status 1A)

    Status 1A designates patients with acute liver failure and predicted survival less than 7 days without transplant, conferring highest priority.

  4. Which lung function parameter is the primary determinant when evaluating a potential lung donor for suitability?

    Answer: PaO2/FiO2 ratio (P/F ratio) ≥300

    A P/F ratio ≥300 on 100% FiO2 and 5 cmH2O PEEP indicates adequate gas exchange and donor lung viability.

  5. Following pancreas transplantation, which laboratory value is the most direct indicator of graft exocrine function failure?

    Answer: Urine amylase (in bladder-drained grafts)

    In bladder-drained pancreas transplants, a fall in urine amylase is the earliest and most sensitive marker of exocrine graft rejection.

  6. A heart transplant candidate has a panel reactive antibody (PRA) of 85%. What is the primary clinical implication?

    Answer: High likelihood of hyperacute rejection without prospective crossmatch

    A high PRA indicates broad sensitization to HLA antigens, significantly increasing the risk of hyperacute rejection if a prospective crossmatch is not performed.

  7. Which preservation solution is most commonly used for kidney and liver procurement during multi-organ procurement?

    Answer: University of Wisconsin (UW) solution

    University of Wisconsin (UW) solution is the gold standard cold storage preservation solution for kidneys, livers, and pancreata due to its oncotic and metabolic protective properties.