CCTC Evaluation and Preparation for Transplant 2

Question 1

Which pulmonary function test value below the threshold typically contraindicates lung transplant evaluation?

Accepted Answer

DLCO < 20% predicted

Answer

A DLCO below 20% predicted is associated with extremely high post-operative mortality and is generally considered a contraindication to lung transplant.

Question 2

During pretransplant cardiac evaluation for a kidney transplant candidate, which finding would most likely EXCLUDE the patient from listing?

Accepted Answer

Ejection fraction of 35% unresponsive to optimization

Answer

Severe left ventricular dysfunction with an EF of 35% that does not improve with medical optimization is a relative-to-absolute contraindication for kidney transplant due to perioperative cardiac risk.

Question 3

A liver transplant candidate has a MELD-Na score of 28. What does this primarily indicate?

Accepted Answer

Higher 90-day mortality risk and greater urgency for transplant

Answer

MELD-Na scores reflect 90-day waitlist mortality; higher scores indicate sicker patients who are prioritized for organ allocation.

Question 4

Which immunological test is performed to detect preformed antibodies against HLA antigens in a transplant candidate?

Accepted Answer

Panel Reactive Antibody (PRA) testing

Answer

PRA testing identifies the breadth of a candidate's sensitization by detecting preformed anti-HLA antibodies that could cause hyperacute rejection.

Question 5

What is the primary purpose of a virtual crossmatch in transplant evaluation?

Accepted Answer

To compare donor HLA typing against recipient antibody profiles without mixing actual cells

Answer

Virtual crossmatch uses donor HLA typing and recipient DSA data to predict crossmatch results without requiring physical serum and cells, enabling faster organ placement.

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC Evaluation and Preparation for Transplant 2