SM Risk Management & Mitigation 3

Question 1

A laboratory worker is found to have a latex allergy. Which risk mitigation step is MOST appropriate for continued safe laboratory participation?

Accepted Answer

Provide nitrile or other latex-free gloves and post latex-free zone signage

Answer

Substituting latex gloves with nitrile or vinyl alternatives and designating latex-free zones eliminates the allergen exposure while keeping the worker operational.

Question 2

Select agents and toxins regulated under 42 CFR Part 73 must be inventoried with what minimum frequency?

Accepted Answer

Weekly

Answer

42 CFR Part 73 requires that registered entities reconcile select agent and toxin inventories at least annually, though most programs perform more frequent checks.

Question 3

Which type of biological safety cabinet (BSC) provides protection to BOTH the worker and the product but does NOT protect the environment from exhaust?

Accepted Answer

Class II Type A2 BSC recirculating to room

Answer

Class II Type A2 cabinets recirculate 70% of air through HEPA filters back into the room, protecting the worker and product but not the environment from volatile hazardous chemicals.

Question 4

What is the PRIMARY purpose of a biosafety officer (BSO) conducting periodic laboratory inspections?

Accepted Answer

To identify unsafe practices and ensure regulatory compliance before incidents occur

Answer

BSO inspections proactively identify deviations from safe practices, containment requirements, and regulatory standards, preventing incidents rather than responding to them.

Question 5

An aerosol-generating procedure involving a Risk Group 3 agent must be performed in which minimum containment device?

Accepted Answer

A Class II BSC or equivalent containment

Answer

Aerosol-generating procedures with Risk Group 3 agents require a certified Class II or higher BSC (or equivalent primary containment) to capture infectious aerosols before worker exposure.

(SM) Specialist in Microbiology Practice Test

(SM) Specialist in Microbiology Practice Test

SM Risk Management & Mitigation 3