Physician Assistant Dermatologic System Disorders 4

Question 1

An 80-year-old has tense, pruritic bullae on the flexural thighs and abdomen; Nikolsky sign is negative and immunofluorescence shows linear IgG and C3 at the basement membrane. What is the diagnosis?

Accepted Answer

Bullous pemphigoid

Answer

Bullous pemphigoid causes subepidermal tense bullae in the elderly with linear IgG/C3 deposition at the BMZ.

Question 2

A patient with celiac disease has intensely pruritic grouped vesicles on the elbows and buttocks. Which medication provides rapid symptom relief?

Accepted Answer

Dapsone

Answer

Dermatitis herpetiformis responds rapidly to dapsone, while a strict gluten-free diet is the long-term treatment.

Question 3

Rough, sandpaper-like scaly erythematous macules on the sun-exposed scalp of a fair-skinned 70-year-old are precursors to which malignancy?

Accepted Answer

Squamous cell carcinoma

Answer

Actinic keratoses are premalignant lesions that can progress to squamous cell carcinoma.

Question 4

A patient has a bright red, raised, sharply demarcated, indurated plaque on the cheek with fever. Which organism is most likely?

Accepted Answer

Streptococcus pyogenes

Answer

Erysipelas involves the upper dermis and superficial lymphatics and is most often caused by group A streptococcus.

Question 5

A patient presents 8 hours after a cat bite to the hand with erythema and swelling. What is the most appropriate oral antibiotic?

Accepted Answer

Amoxicillin-clavulanate

Answer

Amoxicillin-clavulanate covers Pasteurella multocida, anaerobes, and staphylococci from animal bites.

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Physician Assistant Dermatologic System Disorders 4