Physician Assistant Dermatologic System Disorders 3

Question 1

Which histologic feature is the most important prognostic factor in a newly diagnosed localized cutaneous melanoma?

Accepted Answer

Breslow thickness

Answer

Breslow depth (thickness in mm) is the strongest prognostic factor for localized melanoma and guides staging.

Question 2

A family presents with intensely pruritic papules in finger web spaces and burrows on the wrists, worse at night. What is first-line treatment?

Accepted Answer

Permethrin 5% cream applied neck down, repeated in 1 week

Answer

Permethrin 5% is first-line for scabies, with treatment of all close contacts and a repeat application in 7-14 days.

Question 3

A 28-year-old has tender red nodules on both anterior shins and bilateral hilar lymphadenopathy on chest x-ray. Which condition is most likely?

Accepted Answer

Sarcoidosis

Answer

Erythema nodosum with bilateral hilar adenopathy (Löfgren syndrome) suggests sarcoidosis.

Question 4

A patient has pruritic, purple, polygonal, flat-topped papules on the wrists with fine white lacy lines (Wickham striae). Which infection should be screened for?

Accepted Answer

Hepatitis C

Answer

Lichen planus has a well-documented association with hepatitis C infection.

Question 5

Which acne medication requires enrollment in the iPLEDGE program with two forms of contraception and monthly pregnancy tests?

Accepted Answer

Isotretinoin

Answer

Isotretinoin is highly teratogenic, so US prescribing is restricted through iPLEDGE.

Physician Assistant Practice Test

Physician Assistant Practice Test

Physician Assistant Dermatologic System Disorders 3