Physician Assistant Physician Assistant Musculoskeletal System Disorders 3

Question 1

A 70-year-old woman sustains a hip fracture after a minor fall. DEXA shows a T-score of -3.1. Which bisphosphonate is FDA-approved for reducing fracture risk in postmenopausal osteoporosis?

Accepted Answer

Alendronate

Answer

Alendronate is a bisphosphonate FDA-approved for treating postmenopausal osteoporosis and reducing vertebral, hip, and nonvertebral fracture risk.

Question 2

Which physical exam finding is most specific for medial meniscus tear?

Accepted Answer

Positive McMurray test with medial joint line pain

Answer

The McMurray test with clicking and medial joint line pain during knee extension from a flexed position is most specific for a medial meniscus tear.

Question 3

What is the most common cause of osteomyelitis in adults in the United States?

Accepted Answer

Staphylococcus aureus

Answer

Staphylococcus aureus is the most common causative organism of osteomyelitis in adults, accounting for the majority of hematogenous and contiguous cases.

Question 4

A 45-year-old male presents with low back pain and morning stiffness lasting more than 1 hour that improves with exercise. HLA-B27 is positive. What is the most likely diagnosis?

Accepted Answer

Ankylosing spondylitis

Answer

Ankylosing spondylitis is a seronegative spondyloarthropathy strongly associated with HLA-B27, presenting with inflammatory back pain, prolonged morning stiffness relieved by activity.

Question 5

Which medication class is contraindicated in patients with gout who are taking allopurinol and develop a skin rash?

Accepted Answer

Ampicillin-class antibiotics

Answer

Aminopenicillins (ampicillin, amoxicillin) increase the risk of severe drug reactions including Stevens-Johnson syndrome when used with allopurinol.

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Physician Assistant Physician Assistant Musculoskeletal System Disorders 3