Parkinson's Disease 4

Question 1

What percentage of Parkinson's disease cases are estimated to be caused by genetic mutations?

Accepted Answer

5–10%

Answer

Approximately 5–10% of Parkinson's disease cases are linked to identified genetic mutations, while the majority are idiopathic (unknown cause).

Question 2

Mutations in which gene are the most common genetic cause of Parkinson's disease?

Accepted Answer

LRRK2

Answer

Mutations in the LRRK2 (leucine-rich repeat kinase 2) gene are the most common known genetic cause of Parkinson's disease.

Question 3

Which environmental exposure has been most consistently associated with an increased risk of Parkinson's disease?

Accepted Answer

Pesticide and herbicide exposure

Answer

Exposure to pesticides and herbicides, such as rotenone and paraquat, has been the most consistently identified environmental risk factor for Parkinson's disease.

Question 4

Which of the following is considered PROTECTIVE against developing Parkinson's disease based on epidemiological studies?

Accepted Answer

Caffeine consumption

Answer

Multiple epidemiological studies have found that caffeine consumption is inversely associated with Parkinson's disease risk, suggesting a protective effect.

Question 5

What is the average age of onset for Parkinson's disease?

Accepted Answer

Around 60 years old

Answer

The average age of onset for Parkinson's disease is approximately 60 years old, though young-onset PD can occur before age 50.

Parkinson's Practice Test

Parkinson's Practice Test

Parkinson's Disease 4