Parkinson's Parkinson's Mental Health and Cognitive Changes

Question 1

What percentage of Parkinson's disease patients eventually develop Parkinson's disease dementia (PDD)?

Accepted Answer

60-80%

Answer

10-20%

Answer

30-50%

Answer

90-100%

Question 2

Which cognitive domain is MOST commonly affected in the early stages of Parkinson's disease?

Accepted Answer

Executive function

Answer

Language and verbal fluency

Answer

Long-term episodic memory

Answer

Auditory processing

Question 3

What term describes mild cognitive impairment in Parkinson's disease that does not yet meet criteria for dementia?

Accepted Answer

PD-MCI

Answer

Parkinson's disease dementia (PDD)

Answer

Dementia with Lewy bodies (DLB)

Answer

Vascular cognitive impairment

Question 4

Which neurotransmitter deficiency, beyond dopamine, most significantly contributes to cognitive decline in Parkinson's disease?

Accepted Answer

Acetylcholine

Answer

Serotonin

Answer

GABA

Answer

Glutamate

Question 5

How is Parkinson's disease dementia (PDD) clinically distinguished from Dementia with Lewy Bodies (DLB)?

Accepted Answer

Dementia occurs more than 1 year after PD motor onset in PDD, within 1 year or before in DLB

Answer

PDD precedes motor symptoms; DLB always follows them

Answer

PDD only affects memory; DLB only affects movement

Answer

There is no clinical distinction between the two

Question 6

Which medication class is generally AVOIDED in Parkinson's patients with cognitive impairment because it worsens confusion?

Accepted Answer

Anticholinergic medications

Answer

Carbidopa-levodopa

Answer

MAO-B inhibitors

Answer

Amantadine at standard doses

Question 7

Which medication is FDA-approved specifically for treating dementia in Parkinson's disease?

Accepted Answer

Rivastigmine

Answer

Memantine

Answer

Donepezil

Answer

Galantamine