Neuropathy Diabetic Neuropathy

Question 1

What is the most common form of diabetic neuropathy?

Accepted Answer

Distal symmetric polyneuropathy

Answer

Distal symmetric polyneuropathy is the most prevalent form, affecting the feet and hands in a stocking-glove pattern.

Question 2

The stocking-glove pattern of sensory loss in diabetic neuropathy reflects damage to which fiber types first?

Accepted Answer

Small unmyelinated C fibers and Aδ fibers first

Answer

Small nerve fibers (C and Aδ) are damaged early in diabetic neuropathy, causing pain and temperature loss before large-fiber signs appear.

Question 3

Which HbA1c target is recommended to slow the progression of diabetic neuropathy in non-elderly adults with type 1 diabetes?

Accepted Answer

Below 7%

Answer

Maintaining HbA1c below 7% significantly reduces the risk and progression of diabetic peripheral neuropathy.

Question 4

Diabetic amyotrophy (proximal neuropathy) most characteristically presents with which symptom?

Accepted Answer

Severe unilateral thigh pain and weakness

Answer

Diabetic amyotrophy presents with acute, severe, often unilateral pain and weakness in the proximal leg muscles.

Question 5

Which first-line medication is FDA-approved for painful diabetic peripheral neuropathy?

Accepted Answer

Pregabalin

Answer

Pregabalin (Lyrica) is FDA-approved for painful diabetic peripheral neuropathy and has strong clinical trial evidence.

Neuropathy Practice Test