OSCE OSCE Pharmacology and Medication Administration 3

Question 1

What is the antidote for benzodiazepine overdose?

Accepted Answer

Flumazenil

Answer

Flumazenil is a competitive benzodiazepine receptor antagonist used to reverse benzodiazepine-induced sedation.

Question 2

A patient receiving heparin infusion develops a platelet count drop from 280,000 to 60,000 over 5 days. What condition should be suspected?

Accepted Answer

Heparin-induced thrombocytopenia (HIT)

Answer

A 50% or greater platelet drop occurring 5–10 days after heparin initiation is classic for HIT, an immune-mediated prothrombotic condition.

Question 3

Which route of administration provides the fastest onset of drug action in emergency situations?

Accepted Answer

Intravenous

Answer

Intravenous administration delivers the drug directly into the bloodstream, providing the fastest onset of action.

Question 4

A patient is prescribed metformin for type 2 diabetes. Which condition is an absolute contraindication?

Accepted Answer

eGFR of 35 mL/min/1.73m²

Answer

Metformin is contraindicated when eGFR falls below 30 mL/min/1.73m² due to risk of lactic acidosis; caution is advised at eGFR 30–45.

Question 5

When administering an IM injection in the deltoid muscle, what is the maximum volume that should be injected?

Accepted Answer

2 mL

Answer

The deltoid can safely accommodate up to 2 mL of medication; larger volumes should be given in the vastus lateralis or ventrogluteal site.

OSCE Practice Test