OCN Cancer Treatment Modalities

Question 1

Which chemotherapy agent is classified as an alkylating agent?

Accepted Answer

Cyclophosphamide

Answer

Cyclophosphamide is an alkylating agent that works by cross-linking DNA strands to prevent cell replication.

Question 2

What is the primary mechanism of action of taxanes such as paclitaxel?

Accepted Answer

Stabilizing microtubules to prevent mitosis

Answer

Taxanes like paclitaxel stabilize microtubules, preventing their disassembly and thus blocking cell division.

Question 3

A patient receiving external beam radiation develops brisk erythema and moist desquamation. This is classified as what grade of acute skin toxicity per CTCAE?

Accepted Answer

Grade 3

Answer

Moist desquamation is CTCAE Grade 3 radiation dermatitis, requiring wound care and possible treatment interruption.

Question 4

Which route of administration is used for intrathecal chemotherapy?

Accepted Answer

Into the cerebrospinal fluid space

Answer

Intrathecal chemotherapy is injected directly into the cerebrospinal fluid via lumbar puncture or Ommaya reservoir to treat or prevent CNS disease.

Question 5

What is the nadir in the context of chemotherapy administration?

Accepted Answer

The point of lowest blood cell counts after chemotherapy

Answer

The nadir is the lowest point of blood counts (especially neutrophils) following chemotherapy, typically occurring 7–14 days after treatment.

OCN Exam Practice Test

OCN Exam Practice Test

OCN Cancer Treatment Modalities