OCN Cancer Treatment Modalities 3

Question 1

Which immune checkpoint inhibitor targets PD-1?

Accepted Answer

Pembrolizumab

Answer

Pembrolizumab (Keytruda) is a monoclonal antibody that targets the PD-1 receptor on T cells, restoring anti-tumor immunity.

Question 2

A patient on a VEGFR tyrosine kinase inhibitor (TKI) develops hypertension. The nurse should recognize this as:

Accepted Answer

A predictable on-target side effect

Answer

Hypertension is a predictable, on-target side effect of VEGFR TKIs because VEGF normally promotes vasodilation.

Question 3

What is the term for giving chemotherapy before the primary surgical procedure to shrink a tumor?

Accepted Answer

Neoadjuvant therapy

Answer

Neoadjuvant therapy is given before surgery to reduce tumor size and potentially allow for less extensive surgical resection.

Question 4

Which of the following is the correct definition of brachytherapy?

Accepted Answer

Radioactive source placed inside or near the tumor

Answer

Brachytherapy involves placing a radioactive source directly inside or adjacent to the tumor, delivering high local doses.

Question 5

A nurse is preparing to administer rituximab infusion. Which pre-medication is typically given to reduce infusion reactions?

Accepted Answer

Acetaminophen and diphenhydramine

Answer

Acetaminophen and diphenhydramine are standard pre-medications before rituximab to reduce fever and hypersensitivity infusion reactions.

OCN Exam Practice Test