OCC Administration & Safety Protocols 3

Question 1

A patient's chemotherapy cycle requires dose reduction due to a creatinine clearance of 35 mL/min. Which agent most commonly requires renal dose adjustment?

Accepted Answer

Carboplatin

Answer

Carboplatin dosing is calculated using the Calvert formula based on creatinine clearance (GFR), making renal function a direct determinant of the dose.

Question 2

Which practice best prevents catheter-related bloodstream infections (CRBSIs) during chemotherapy administration via a central line?

Accepted Answer

Using maximal sterile barrier precautions during line access

Answer

Maximal sterile barrier precautions—sterile gloves, gown, mask, cap, and large drape—are the evidence-based standard for preventing CRBSIs during line access.

Question 3

A nurse discovers a chemotherapy spill on a countertop. After donning PPE, what is the correct order for spill cleanup?

Accepted Answer

Contain the spill, absorb the liquid, clean the area, decontaminate, dispose in hazardous waste

Answer

The correct spill response sequence is: contain > absorb > clean > decontaminate > dispose in chemotherapy waste containers while wearing full PPE throughout.

Question 4

Which vesicant chemotherapy agent requires an antidote (dexrazoxane) if extravasation occurs?

Accepted Answer

Doxorubicin (anthracycline)

Answer

Dexrazoxane (Totect) is the FDA-approved antidote specifically for anthracycline extravasation to prevent severe tissue necrosis.

Question 5

What is the purpose of using a luer-lock connection rather than a slip-tip connection for chemotherapy administration sets?

Accepted Answer

It prevents accidental disconnection and drug spillage

Answer

Luer-lock connections are mandatory for chemotherapy tubing because they screw securely into place, preventing accidental disconnection and potential drug exposure.

(OCC) Oncology Chemotherapy Certification Practice Test

(OCC) Oncology Chemotherapy Certification Practice Test

OCC Administration & Safety Protocols 3