OCC OCC Chemotherapy-Induced Side Effects Management

Question 1

A patient receiving cisplatin-based chemotherapy develops a serum creatinine of 2.1 mg/dL. Which intervention is the highest priority?

Accepted Answer

Hold the next cisplatin dose and notify the oncologist

Answer

Administer sodium bicarbonate IV

Answer

Increase the infusion rate to clear the drug faster

Answer

Administer furosemide immediately

Question 2

Which antiemetic class is MOST effective for preventing acute chemotherapy-induced nausea and vomiting (CINV) caused by highly emetogenic regimens?

Accepted Answer

5-HT3 receptor antagonists (ondansetron)

Answer

Dopamine antagonists (metoclopramide)

Answer

Antihistamines (diphenhydramine)

Answer

Corticosteroids alone

Question 3

A patient on doxorubicin complains of mouth sores and is unable to eat. The nurse grades the mucositis as Grade 3. Which intervention is appropriate?

Accepted Answer

Initiate parenteral nutrition and notify the provider for dose modification

Answer

Encourage hot liquids to stimulate saliva

Answer

Apply petroleum jelly to the lips only

Answer

Rinse with commercial mouthwash containing alcohol

Question 4

Which finding would MOST concern the oncology nurse when caring for a patient experiencing chemotherapy-induced peripheral neuropathy (CIPN)?

Accepted Answer

Inability to button a shirt or walk without assistance

Answer

Mild tingling in fingertips

Answer

Temporary numbness after infusion

Answer

Sensitivity to cold during oxaliplatin infusion

Question 5

A patient receiving irinotecan develops profuse watery diarrhea 12 hours after infusion. What is the nurse's priority action?

Accepted Answer

Administer loperamide per protocol and monitor hydration status

Answer

Encourage increased fluid intake and reassure the patient

Answer

Prepare for immediate hospitalization

Answer

Administer atropine for late-onset diarrhea

Question 6

Which lab value is the MOST critical to monitor for bone marrow suppression in a patient receiving myelosuppressive chemotherapy?

Accepted Answer

Absolute neutrophil count (ANC)

Answer

Serum albumin

Answer

Serum sodium

Answer

Total bilirubin