OCC Study Guide 2026
Everything you need to pass the OCC exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
OCC exam key facts
📋 OCC Exam Format at a Glance
📚 OCC Topics to Study (22)
✍️ Sample OCC Questions & Answers
1. What is the first procedural step in manufacturing autologous CAR-T cell therapy for a patient?
Leukapheresis to collect the patient's own T cells is the first manufacturing step; these cells are then genetically engineered to express the chimeric antigen receptor.
2. A patient with a new PICC line develops sudden onset of dyspnea, hypotension, and a 'sucking' sound during catheter manipulation. What complication is occurring?
Air embolism can occur during open central catheter manipulation and presents with sudden dyspnea, hypotension, and a mill-wheel murmur or sucking sound.
3. A nurse notes an unexpected serious adverse event in a patient on a clinical trial. What is the MOST important immediate action?
Serious adverse events must be documented, immediately reported to the PI, and captured in the adverse event reporting system per the protocol's safety monitoring plan.
4. A patient's oncologist recommends a treatment listed as Category 1 in the NCCN Guidelines. What does this designation mean?
NCCN Category 1 designations indicate high-level evidence (usually from RCTs) with uniform consensus among NCCN panel members supporting the recommendation.
5. Atezolizumab differs from pembrolizumab and nivolumab in that it targets which molecule?
Atezolizumab targets PD-L1 (the ligand) rather than PD-1 (the receptor), blocking the interaction from the antigen-presenting or tumor cell side.
6. Which factor MOST increases a patient's risk for chemotherapy extravasation injury?
Fragile veins with multiple prior cannulation sites have compromised integrity, significantly increasing the risk of extravasation during chemotherapy infusion.
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📖 OCC Guides & Articles
What Practice Test Geeks adds beyond an AI chat for OCC
An AI chatbot can quiz you, but it can't reproduce the exam conditions or keep your record. Here you get:
- A timed, full-length OCC mock exam — 75 questions in 90 minutes with a 80% pass mark, modeled on the official exam's question count and time limit, followed by a score report broken down by exam domain.
- A fixed OCC question bank: the same test every attempt, so your score is comparable from one try to the next instead of changing with every regenerated quiz.
- Progress saved on your device: completed tests, scores and missed questions stay in My Progress, so you can retake only what you got wrong.
- A printable OCC cheat sheet you can print or save as a PDF.
- OCC flashcards built from the same question bank.
- Free OCC practice tests with the correct answer shown after each question.
How this page was made: written with AI tools and published by Nathan Beja, founder of Practice Test Geeks, who is responsible for its content. Exam facts are checked against the official sources listed below. Not reviewed by a subject-matter expert. Editorial policy
Sources & references
Exam facts on this page (fees, format, dates, passing scores) are checked against these official sources; the date is our last check. Editorial policy
- ons.org — Test delivery, fees, passing score, retake policy, test dates, score validity, late registration, renewal · verified Oct 2026