OCC Clinical Trials & Evidence-Based Practice Flashcards
6 cards from real OCC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 OCC Clinical Trials & Evidence-Based Practice flashcards as text
Which study design provides the HIGHEST level of evidence for evaluating the effectiveness of a new chemotherapy regimen?
Answer: Randomized controlled trial (RCT)
The randomized controlled trial is the gold standard study design for establishing causal efficacy by minimizing bias through randomization and controlled comparison.
A patient's oncologist recommends a treatment listed as Category 1 in the NCCN Guidelines. What does this designation mean?
Answer: High-level evidence with uniform consensus that the recommendation is appropriate
NCCN Category 1 designations indicate high-level evidence (usually from RCTs) with uniform consensus among NCCN panel members supporting the recommendation.
The oncology nurse is reviewing a study that reports a hazard ratio (HR) of 0.65 with a 95% CI of 0.50-0.85 for a new drug versus placebo. What does this mean?
Answer: The new drug reduces the risk of the event by 35%, and this is statistically significant
An HR of 0.65 means a 35% reduction in the hazard (risk) of the event; since the 95% CI (0.50-0.85) does not cross 1.0, the result is statistically significant.
Which quality improvement model is MOST commonly used in oncology nursing practice to implement and evaluate evidence-based changes?
Answer: PDSA (Plan-Do-Study-Act) cycle
The PDSA cycle is the most widely used quality improvement model in nursing and oncology practice for iterative, evidence-based practice change.
A nurse wants to find the best evidence for managing chemotherapy-induced nausea. Which resource provides the MOST credible, peer-reviewed clinical practice guidelines?
Answer: ASCO, ONS, or NCCN clinical practice guidelines
Professional organization guidelines from ASCO, ONS, and NCCN are developed through systematic evidence review and expert consensus, providing the most credible clinical practice guidance.
A nurse is implementing a new evidence-based protocol for central line care. Which approach BEST demonstrates integration of evidence-based practice (EBP)?
Answer: Combining current best evidence, clinical expertise, and patient preferences to guide implementation
Evidence-based practice integrates the best available research evidence with clinical expertise and individual patient values and preferences.
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