A 45-year-old woman presents with bilateral wrist pain, swan-neck deformities, and positive anti-CCP antibodies. Which mechanism best explains joint destruction in her condition?
-
A
Pannus formation eroding cartilage and bone
-
B
Urate crystal deposition in synovial fluid
-
C
Calcium pyrophosphate deposition in cartilage
-
D
Bacterial seeding of the joint space