FPGEE Trivia FPGEE Exam 5

Question 1

What is the first-line treatment for community-acquired pneumonia in a healthy outpatient adult with no comorbidities?

Accepted Answer

Azithromycin or doxycycline

Answer

IDSA/ATS guidelines recommend azithromycin or doxycycline as first-line for healthy outpatients with CAP.

Question 2

Which drug class is associated with causing Stevens-Johnson syndrome as a serious adverse effect?

Accepted Answer

Sulfonamide antibiotics

Answer

Sulfonamide antibiotics (e.g., trimethoprim-sulfamethoxazole) are classically associated with Stevens-Johnson syndrome.

Question 3

What is the clinical significance of a drug with a narrow therapeutic index?

Accepted Answer

Small dosage changes can lead to toxicity or subtherapeutic levels

Answer

Narrow therapeutic index drugs require close monitoring because the toxic dose is close to the therapeutic dose.

Question 4

Which type of drug interaction occurs when one drug alters the renal tubular secretion of another?

Accepted Answer

Pharmacokinetic-excretion interaction

Answer

Alterations in renal tubular secretion represent a pharmacokinetic interaction at the excretion stage.

Question 5

What is the primary difference between bacteriostatic and bactericidal antibiotics?

Accepted Answer

Bacteriostatic drugs inhibit growth; bactericidal drugs kill bacteria

Answer

Bacteriostatic agents inhibit bacterial growth (relying on host immunity) while bactericidal agents directly kill bacteria.

FPGEE Exam Practice Test