FPGEE FPGEE MCQ Exam 5

Question 1

A pharmacist is counseling a patient on how to administer insulin glargine. Which statement is correct?

Accepted Answer

It must be administered once daily at any consistent time and never mixed

Answer

Insulin glargine is a peakless basal insulin given once daily and cannot be mixed with other insulins because altering its pH destroys its slow-release properties.

Question 2

Which vitamin deficiency is MOST likely in a strict vegan who has not taken any supplements for 5 years?

Accepted Answer

Vitamin B12 (cobalamin)

Answer

Vitamin B12 is found almost exclusively in animal products; strict vegans are at high risk of B12 deficiency leading to megaloblastic anemia and neuropathy.

Question 3

A drug follows first-order kinetics with a half-life of 6 hours. Approximately how long until steady-state is reached with regular dosing?

Accepted Answer

30 hours

Answer

Steady-state is achieved after approximately 4–5 half-lives; 5 × 6 hours = 30 hours.

Question 4

Which antifungal mechanism involves binding to ergosterol and forming pores in the fungal cell membrane?

Accepted Answer

Polyenes (amphotericin B)

Answer

Amphotericin B and other polyenes bind directly to ergosterol in the fungal membrane, forming pores that cause leakage of intracellular contents.

Question 5

Under the Drug Quality and Security Act (DQSA), which category of compounders is regulated directly by the FDA as an outsourcing facility?

Accepted Answer

503B outsourcing facilities producing large-scale sterile preparations

Answer

503B outsourcing facilities voluntarily register with the FDA, allowing large-scale compounding of sterile preparations without patient-specific prescriptions under federal oversight.

FPGEE Exam Practice Test

FPGEE Exam Practice Test

FPGEE FPGEE MCQ Exam 5