FPGEE FPGEE MCQ Exam 4

Question 1

A pharmacist receives a prescription for oxycodone 5 mg #30. The DEA schedule of oxycodone requires how many days' supply maximum per prescription in most US states?

Accepted Answer

No federal day-supply limit exists for Schedule II

Answer

Federally, the DEA does not impose a day-supply limit on Schedule II prescriptions; however, individual states may set their own limits.

Question 2

Which mechanism explains the therapeutic action of metformin in type 2 diabetes?

Accepted Answer

Activates AMPK, reducing hepatic glucose output

Answer

Metformin primarily activates AMP-activated protein kinase (AMPK), suppressing hepatic gluconeogenesis and glycogenolysis to lower blood glucose.

Question 3

A patient on warfarin begins taking high-dose vitamin E supplements. What is the expected effect on INR?

Accepted Answer

Increased INR due to inhibition of vitamin K-dependent clotting factors

Answer

High-dose vitamin E impairs vitamin K–dependent carboxylation of clotting factors II, VII, IX, and X, potentiating warfarin's anticoagulant effect and raising INR.

Question 4

Which isomer of albuterol is responsible for its bronchodilatory therapeutic effect?

Accepted Answer

R-albuterol (levalbuterol)

Answer

R-albuterol (levalbuterol) is the eutomer that binds beta-2 receptors and causes bronchodilation; S-albuterol may contribute to bronchoconstriction.

Question 5

A patient with Parkinson's disease taking levodopa/carbidopa develops end-of-dose wearing off. Which add-on agent BEST extends levodopa effect?

Accepted Answer

Entacapone (COMT inhibitor)

Answer

Entacapone inhibits COMT, preventing peripheral breakdown of levodopa and extending its duration of action to reduce wearing-off.

FPGEE Exam Practice Test

FPGEE Exam Practice Test

FPGEE FPGEE MCQ Exam 4