FPGEE Drug Information 5

Question 1

Which component of the PICO framework represents the standard treatment or comparator group?

Accepted Answer

C – Comparison

Answer

In the PICO framework, 'C' stands for Comparison, representing the alternative treatment or placebo against which the intervention is evaluated.

Question 2

A pharmacist is asked whether a drug causes QT prolongation. Which specialized resource is BEST suited to answer this?

Accepted Answer

CredibleMeds (AzCERT QTDrugs List)

Answer

CredibleMeds (maintained by AzCERT) maintains the most comprehensive, evidence-based risk categorization for drug-induced QT prolongation.

Question 3

What is publication bias in the context of drug information evaluation?

Accepted Answer

Preferential publication of studies with positive or statistically significant results

Answer

Publication bias is the tendency for studies with positive or statistically significant results to be published more frequently than those with null or negative results.

Question 4

Which measure of central tendency is MOST affected by outliers in a dataset?

Accepted Answer

Mean

Answer

The mean is most sensitive to outliers because it incorporates the actual value of every data point in its calculation.

Question 5

A drug information response recommends a lower dose for a patient with renal impairment. Which primary resource BEST supports this recommendation?

Accepted Answer

Lexicomp Renal Disease Dosing or the FDA package insert renal dosing section

Answer

The FDA package insert's renal dosing section and Lexicomp's renal disease dosing guidance provide the most directly applicable evidence-based recommendations for dose adjustment.

FPGEE Exam Practice Test

FPGEE Exam Practice Test

FPGEE Drug Information 5