DO Practice Test 2026 — free exam prep

DO Practice Test

Updated November 2026
Nov 1, 202611 min read

Facts verified Nov 1, 2026 against National Board of Osteopathic Medical Examiners

If you dream of becoming an osteopathic physician in the United States, you must pass the DO (Doctor of Osteopathy) Test. This is also known as the Comprehensive Osteopathic Medical Licensing Examination (COMLEX). It’s a key step toward getting your medical license. This test checks your knowledge, skills, and readiness to practice osteopathic medicine. The DO test makes sure you have what it takes to care for patients well. If you’re getting ready for the COMLEX exam or just want to know more about osteopathic licensing, this guide is for you. It will help you understand the DO test and its role in your future as a DO. Practice with the free DO - Doctor of Osteopathy practice test on PracticeTestGeeks (7 questions with answer explanations).

  • COMLEX-USA Level 1 and Level 2-CE each have 320 single-best-answer multiple-choice questions.[1]
  • COMLEX-USA Level 3 currently has 420 multiple-choice questions and 26 clinical decision-making cases; from January 13, 2027 it has 240 multiple-choice questions and 16 CDM cases.[1]
  • COMLEX-USA Level 1 and Level 2-CE are one-day exams with two timed 4-hour sessions, 8 hours in total.[1]
  • The minimum passing score for COMLEX-USA Level 1 and Level 2-CE is 400.[2]
  • The minimum passing score for COMLEX-USA Level 3 is 350.[2]
  • The COMLEX-USA Level 1 exam fee is $745.[3]
  • The COMLEX-USA Level 2-CE exam fee is $745.[3]
  • COMLEX-USA examinations are computer-based and delivered by the NBOME's partner Pearson at Pearson test centers.[4]
  • COMLEX-USA levels must be taken in order: Level 1 after the first year at a COCA-accredited college of osteopathic medicine, Level 2-CE after passing Level 1 and completing the second year, and Level 3 after graduating with a DO and passing Levels 1 and 2-CE.[5]

Numbers in brackets link to the official sources listed under Sources & last verified. Dates that have passed are removed automatically.

DO Exam at a Glance

ItemDetailSource · Verified
Number of questions (Level 1 / Level 2-CE)320 multiple-choice questions[1]National Board of Osteopathic Medical Examiners · Oct 26, 2026
Number of questions (Level 3)420 MCQs + 26 CDM cases (240 MCQs + 16 CDM cases from Jan 13, 2027)[1]National Board of Osteopathic Medical Examiners · Oct 26, 2026
Time limit (Level 1 / Level 2-CE)8 hours (two 4-hour sessions)[1]National Board of Osteopathic Medical Examiners · Oct 26, 2026
Passing score (Level 1 / Level 2-CE)400[2]National Board of Osteopathic Medical Examiners · Oct 26, 2026
Passing score (Level 3)350[2]National Board of Osteopathic Medical Examiners · Oct 26, 2026
Exam fee (Level 1)$745[3]National Board of Osteopathic Medical Examiners · Oct 26, 2026
Exam fee (Level 2-CE)$745[3]National Board of Osteopathic Medical Examiners · Oct 26, 2026
Exam fee (Level 3)$950[3]National Board of Osteopathic Medical Examiners · Oct 26, 2026
DeliveryComputer-based at Pearson VUE test centers[4]National Board of Osteopathic Medical Examiners · Oct 26, 2026
EligibilitySequential: L1 after year 1 at a COCA-accredited COM; L2-CE after passing L1 + year 2; L3 after DO graduation + passing L1 and L2-CE[5]National Board of Osteopathic Medical Examiners · Oct 26, 2026
Registration opensTypically 6 months before the first testing window[6]National Board of Osteopathic Medical Examiners · Oct 26, 2026

What changed for DO in 2026

  • Oct 26, 2026: Eligibility changed to Sequential: L1 after year 1 at a COCA-accredited COM; L2-CE after passing L1 + year 2; L3 after DO graduation + passing L1 and L2-CE (previously Sequential: L1 after year 1 at a COCA-accredited COM; L2-CE after L1 + year 2; L3 after DO graduation + L1/L2-CE).[5]
  • Oct 26, 2026: Registration opens changed to Typically 6 months before the first testing window (previously Typically 6 months before the first window; open now for all Levels).[6]

Free DO - Doctor of Osteopathy Study Tools

Interactive DO - Doctor of Osteopathy resources on PracticeTestGeeks, free to start:

  • DO Psychiatry and Behavioral Medicine 1 — 7 questions with answer explanations
  • DO - Doctor of Osteopathy flashcards — review key terms and concepts card by card
  • DO - Doctor of Osteopathy study guide — topic-by-topic overview of what the exam covers
  • DO - Doctor of Osteopathy cheat sheet — one-page printable summary for last-minute review

According to National Board of Osteopathic Medical Examiners, “A candidate must meet all of the requirements outlined below. Examinations must be taken in sequence and each Level passed before the candidate is eligible to take the next Level.”[5]

DO content outline and where to practise each area

The content areas below are copied from the official DO content outline published by National Board of Osteopathic Medical Examiners, with the share of the exam each area carries. The right-hand column shows which of our practice sets covers it.

Official content areaWeightPractice on this site
Application of Knowledge for Osteopathic Medical Practice[7]60%Mixed practice tests above
Interpersonal and Communication Skills in the Practice of Osteopathic Medicine[7]3%Mixed practice tests above
Osteopathic Patient Care and Procedural Skills[7]6%Mixed practice tests above
Osteopathic Principles, Practice, and Manipulative Treatment[7]12%Mixed practice tests above
Practice-Based Learning and Improvement in Osteopathic Medical Practice[7]4%Mixed practice tests above
Professionalism in the Practice of Osteopathic Medicine[7]3%Mixed practice tests above
Systems-Based Practice in Osteopathic Medicine[7]2%Mixed practice tests above

DO Practice Test Questions

Prepare for the DO - Doctor of Osteopathy exam with our free practice test modules. Each quiz covers key topics to help you pass on your first try.

DO Bioethics and Medical Law

DO Exam Questions covering Bioethics and Medical Law. Master DO Test concepts for certification prep.

DO Diagnostic Reasoning and Evidence-Based...

Free DO Practice Test featuring Diagnostic Reasoning and Evidence-Based Medicine. Improve your DO Exam score with mock test prep.

DO Osteopathic Manipulative Medicine

DO Mock Exam on Osteopathic Manipulative Medicine. DO Study Guide questions to pass on your first try.

DO Pharmacology and Therapeutics

DO Test Prep for Pharmacology and Therapeutics. Practice DO Quiz questions and boost your score.

DO Preventive Medicine and Public Health

DO Questions and Answers on Preventive Medicine and Public Health. Free DO practice for exam readiness.

DO Psychiatry and Behavioral Medicine

DO Mock Test covering Psychiatry and Behavioral Medicine. Online DO Test practice with instant feedback.

Doctor of Osteopathy Advanced Clinical Ski...

Free DO Quiz on Doctor of Osteopathy Advanced Clinical Skills and Patient Management. DO Exam prep questions with detailed explanations.

Doctor of Osteopathy Clinical Medicine Cog...

DO Practice Questions for Doctor of Osteopathy Clinical Medicine Cognitive and Performance Evaluation. Build confidence for your DO certification exam.

Doctor of Osteopathy Foundational Knowledge

DO Test Online for Doctor of Osteopathy Foundational Knowledge. Free practice with instant results and feedback.

Doctor of Osteopathy Medical Sciences

DO Study Material on Doctor of Osteopathy Medical Sciences. Prepare effectively with real exam-style questions.

Worked examples: how to reason through DO questions

These are practice questions written for this site, not questions from the real exam. Each explanation shows why the right answer is right and why the others are wrong.

Example 1

Question: The Still technique in OMM is best described as which type of combined approach?

  1. Indirect followed by direct with a dynamic thrust
  2. Pure indirect positioning only
  3. Purely passive craniosacral rhythm
  4. Isotonic resistive exercise

Answer: A. Indirect followed by direct with a dynamic thrust

Explanation:

The correct answer is indirect followed by direct with a dynamic thrust. The Still technique first moves the dysfunctional part toward ease, which is the indirect phase, and then carries it through the restrictive barrier with a quick corrective force.

Pure indirect positioning leaves out the direct phase, so it describes only half of the method. Purely passive craniosacral rhythm belongs to a different model of treatment and has no thrust. Isotonic resistive exercise relies on the patient's own muscle contraction against resistance, which is not how this technique works.

The rule to remember is that when a technique name is described as combined, look for both an indirect component and a direct component. Then check how the force is delivered.

Example 2

Question: A 32-year-old veteran presents with intrusive flashbacks, nightmares, hypervigilance, emotional numbing, and avoidance of combat-related stimuli persisting for 6 months post-deployment. What is the first-line pharmacological treatment?

  1. Benzodiazepines
  2. Sertraline or paroxetine
  3. Risperidone
  4. Propranolol

Answer: B. Sertraline or paroxetine

Explanation:

The correct answer is sertraline or paroxetine. The picture is post-traumatic stress disorder: intrusive flashbacks, nightmares, hypervigilance, numbing and avoidance of reminders, lasting 6 months after deployment. SSRIs are the recommended first-line medication, and sertraline and paroxetine are the FDA-approved options.

Benzodiazepines can relieve anxiety briefly but do not treat the core disorder and may worsen outcomes. Risperidone is an antipsychotic and is not a first-line agent for this presentation. Propranolol has been studied to blunt traumatic memory formation, but it is not the established treatment for an existing disorder.

The rule to remember is that for a long-standing trauma-related disorder, start with an SSRI plus trauma-focused therapy rather than a sedative.

Example 3

Question: Counterstrain technique positions the patient to achieve what primary effect?

  1. Relief of tender point pain
  2. Joint cavitation
  3. Fascial unwinding
  4. Lymphatic drainage

Answer: A. Relief of tender point pain

Explanation:

The correct answer is relief of tender point pain. Counterstrain places the patient in a position of comfort that shortens the offending muscle, which lets the tender point settle and the pain ease.

Joint cavitation is the audible release associated with high-velocity thrust techniques, and counterstrain uses no thrust. Fascial unwinding describes myofascial release, where the practitioner follows tissue motion rather than holding a position of comfort. Lymphatic drainage describes lymphatic techniques that move fluid, which is a different goal from treating a tender point.

The rule to remember is to link each technique to its goal. Counterstrain means a tender point, a position of ease and pain relief.

How to use these practice tests

Start with the official material. Read the NBOME content outline and note how the areas are weighted, then set your study time roughly in proportion. The largest area deserves most of your attention, but the smaller areas are quick to improve and are easy to neglect.

Take a short diagnostic set from each subject on this page and write down what you missed. Sort the misses into three groups: facts you did not know, reasoning you got wrong, and questions you misread. Each group needs a different fix. Facts need review, reasoning needs more worked cases, and misreading needs slower reading.

  • Practise osteopathic manipulative medicine in short, regular sessions, because technique names and goals fade quickly without repetition.
  • Read every explanation, including the ones for questions you got right.
  • Redo missed questions after a few days, not straight away.

As test day approaches, move to longer mixed sets from the practice test and sit them without pausing, so you build stamina for the long, session-based exam. Our questions are written by us and are not real exam questions, so treat them as practice for reasoning and recall, not as a prediction of your score. Check the official site for current rules before booking.

Key Takeaways

Free (DO) Doctor of Osteopathy Practice Test Online

  • The DO test, or COMLEX, is the licensing exam for osteopathic physicians in the United States.
  • The exam assesses an individual’s knowledge, skills, and competencies in the field of osteopathic medicine.
  • Passing the DO test is a mandatory requirement for obtaining an osteopathic medical license and practicing as a DO.
  • The exam is divided into multiple levels, each testing different aspects of osteopathic medical knowledge and clinical skills.
  • Proper preparation, including reviewing study materials and practicing sample questions, is crucial for success on the DO test.
DO (Doctor of Osteopathy) Test: What You Need to Know - Doctor of Osteopathy exam preparation

Purpose and Significance of the Exam

Understanding the DO (Doctor of Osteopathy) Test

The DO (Doctor of Osteopathy) Test, also known as the Comprehensive Osteopathic Medical Licensing Examination (COMLEX), is key for osteopathic physicians in the U.S. It checks if they know their stuff, can apply it, and care for patients well. The National Board of Osteopathic Medical Examiners (NBOME) sets the bar high before they can start practicing.

The osteopathic licensing exam tests if a candidate really gets osteopathic medicine. It checks if they can use this knowledge in real-life situations and care for patients fully. Passing the COMLEX is a must for osteopathic board certification and a license to practice in most states.

Eligibility Requirements for DO Candidates

To take the DO (Doctor of Osteopathy) Test, candidates need to finish an accredited osteopathic medical program. They must also meet the NBOME’s educational and training standards. This means graduating from a school approved by the American Osteopathic Association (AOA) or Commission on Osteopathic College Accreditation (COCA) and doing the required clinical work.

  • Graduation from an AOA or COCA-accredited osteopathic medical school
  • Completion of required clinical rotations and residency programs
  • Fulfillment of DO board eligibility criteria established by the NBOME

Future osteopathic physicians must go through the osteopathic medical licensing process. The COMLEX exam is a big step towards becoming a licensed DO (doctor of osteopathy) practitioner.

DO (Doctor of Osteopathy) Test: What You Need to Know - Doctor of Osteopathy certification guide
✅Pros
  • +Validates your knowledge and skills objectively
  • +Increases job market competitiveness
  • +Provides structured learning goals
  • +Networking opportunities with other certified professionals
❌Cons
  • −Study materials can be expensive
  • −Exam anxiety can affect performance
  • −Requires dedicated preparation time
  • −Retake fees apply if you don't pass

Pros and Cons at a Glance

ProsCons
Validates your knowledge and skills objectivelyStudy materials can be expensive
Increases job market competitivenessExam anxiety can affect performance
Provides structured learning goalsRequires dedicated preparation time
Networking opportunities with other certified professionalsRetake fees apply if you don't pass

Sample DO - Doctor of Osteopathy Practice Questions

Try these questions from our free DO - Doctor of Osteopathy practice tests. The correct answer and an explanation follow each question.

  1. What is the fundamental conception of osteopathy?

    • A. That abnormal body functioning arises from structural defects, particularly a lack of free movement in joints near vital nerve roots.
    • B. That diseases are primarily caused by infections.
    • C. That all diseases can be treated with medication.
    • D. That mental health is the only consideration in physical ailments.

Answer: A. That abnormal body functioning arises from structural defects, particularly a lack of free movement in joints near vital nerve roots.

The fundamental conception of osteopathy is that abnormal body functioning often stems from structural defects, particularly restrictions in joint movement near vital nerve roots. This principle, established by A.T. Still, posits that structural integrity is essential for proper physiological function. By restoring free movement and addressing these structural impediments, osteopathy aims to enhance the body's natural healing processes.

  • What does the word "osteopathy" mean?

    • A. A modern term for physical therapy.
    • B. Derived from Greek roots that refer to bone and disease
    • C. A method of treating diseases through surgery.
    • D. A term derived from the Latin meaning "to heal with herbs."
  • Answer: B. Derived from Greek roots that refer to bone and disease

    The word 'osteopathy' originates from Greek roots: 'osteon' meaning bone, and 'pathos' meaning suffering or disease. This etymology reflects the historical emphasis of osteopathic philosophy on the skeletal system and its role in health and illness. While modern osteopathy addresses the entire body, its name points to this foundational understanding.

  • According to Dr. Schleip, what factor contributes to the immediate tissue changes observed with techniques like Myofascial Release (MFR)?

    • A. The presence of a dense network of mechanoreceptors within the fascia.
    • B. Immediate fascial plasticity can be fully explained by the mechanical properties of the fascia.
    • C. The use of heat to relax the fascia before treatment.
    • D. The client's emotional state during the procedure.
  • Answer: A. The presence of a dense network of mechanoreceptors within the fascia.

    Dr. Schleip suggests that immediate tissue changes observed with techniques like Myofascial Release are significantly influenced by the dense network of mechanoreceptors within the fascia. These sensory receptors allow for rapid neurophysiological responses, influencing muscle tone and tissue stiffness through reflex pathways. This explains why changes can be felt almost immediately, rather than solely relying on the slower mechanical properties of fascial stretching.

  • The US Preventive Services Task Force (USPSTF) recommends colorectal cancer screening beginning at what age for average-risk adults?

    • A. 45 years
    • B. 50 years
    • C. 40 years
    • D. 55 years
  • Answer: A. 45 years

    In 2021, the USPSTF updated its recommendation to begin colorectal cancer screening at age 45 for average-risk adults, lowered from the previous age of 50.

    Take the full DO - Doctor of Osteopathy practice test

    What is the purpose and significance of the DO (Doctor of Osteopathy) Test?

    The DO (Doctor of Osteopathy) Test, also known as the Comprehensive Osteopathic Medical Licensing Examination (COMLEX), is key for osteopathic physicians in the U.S. It checks if aspiring DOs know their stuff and can practice medicine well. The National Board of Osteopathic Medical Examiners (NBOME) sets the standards.

    What are the eligibility requirements for taking the DO (Doctor of Osteopathy) Test?

    To take the DO (Doctor of Osteopathy) Test, you must finish an accredited osteopathic medical program. You also need to meet the NBOME’s education and training rules. This means graduating from a school approved by the American Osteopathic Association (AOA) or Commission on Osteopathic College Accreditation (COCA) and doing your clinical rotations and residency.

    What is the structure and components of the DO (Doctor of Osteopathy) Test?

    The DO (Doctor of Osteopathy) Test, or COMLEX, tests your knowledge and skills in osteopathic medicine. It has parts like multiple-choice questions, patient encounters, and tests of osteopathic manipulative medicine (OMM). You need to show you know both the science and practice of osteopathic medicine to pass.

    How can I prepare for the DO (Doctor of Osteopathy) Test?

    To get ready for the DO (Doctor of Osteopathy) Test, make a study plan. Review your course materials, practice your clinical skills, and get used to the exam format. Use practice tests, go to review courses, and ask for advice from DOs to prepare well.

    What is the scoring system for the DO (Doctor of Osteopathy) Test?

    The COMLEX scores range from 1 to 800. A passing score is usually 400-500, depending on the part of the exam. Higher scores mean you did better. Remember, the passing score can change by state, so check your area’s rules.

    How often can I take the DO (Doctor of Osteopathy) Test?

    You can take the COMLEX several times a year, with specific dates and deadlines from the NBOME. You can try up to three times a year, but there’s a limit on lifetime attempts. Make sure to follow the NBOME’s rules and deadlines for your test schedule.

    What happens if I fail the DO (Doctor of Osteopathy) Test?

    If you fail the DO (Doctor of Osteopathy) Test, or COMLEX, you’ll need to retake it. The NBOME gives detailed feedback to help you improve. Many schools and programs offer support for retakes. Stay focused and keep working towards your goal of becoming a licensed osteopathic physician.

    Free (do) Doctor of Osteopathy Practice Test Online guide - Doctor of Osteopathy certification study resource

    Sources & last verified

    1. National Board of Osteopathic Medical Examiners — number of questions, time limit (official source). “320 single-best-answer, multiple-choice questions” Verified Oct 26, 2026.
    2. National Board of Osteopathic Medical Examiners — passing score (official source). “COMLEX-USA Level 1 – 400” Verified Oct 26, 2026 · source checked Oct 26, 2026.
    3. National Board of Osteopathic Medical Examiners — exam fee (official source). “The fee for COMLEX-USA Level 1 is $745.” Verified Oct 26, 2026 · source checked Oct 25, 2026.
    4. National Board of Osteopathic Medical Examiners — delivery (official source). “The NBOME partners with Pearson to deliver your COMLEX-USA examinations.” Verified Oct 26, 2026 · source checked Oct 26, 2026.
    5. National Board of Osteopathic Medical Examiners — eligibility (official source). “A candidate must meet all of the requirements outlined below. Examinations must be taken in sequence and each Level passed before the candidate is eligible…” Verified Oct 26, 2026 · source checked Oct 26, 2026.
    6. National Board of Osteopathic Medical Examiners — registration opens (official source). “Please note that registration for testing dates typically opens six months prior to the start of the first testing window.” Verified Oct 26, 2026 · source checked Oct 25, 2026.
    7. National Board of Osteopathic Medical Examiners — other (official source). “application of knowledge for osteopathic medical practice 60%” Verified Nov 1, 2026.

    How we verify: editorial & fact-checking policy. Report an error: contact us.

    How this page was made: written with AI tools and published by Nathan Beja, founder of Practice Test Geeks, who is responsible for its content. Exam facts are checked against the official sources listed below. Not reviewed by a subject-matter expert. Editorial policy

    Sources & references

    Exam facts on this page (fees, format, dates, passing scores) are checked against these official sources; the date is our last check. Editorial policy

    1. nbome.org — Registration, passing score, exam format, time limit, fees, eligibility, test delivery · verified Oct 2026