CVT CVT Pharmacology & Medication Effects on Vestibular Function 2

Question 1

Which agent is administered intratympanically to chemically ablate vestibular function in refractory Meniere's disease?

Accepted Answer

Gentamicin

Answer

Low-dose intratympanic gentamicin selectively destroys vestibular hair cells while attempting to spare cochlear function, reducing the frequency of drop attacks.

Question 2

Betahistine is thought to benefit Meniere's disease by:

Accepted Answer

Improving microvascular blood flow in the inner ear stria vascularis

Answer

Betahistine is believed to act as an H3 antagonist and H1 agonist, improving cochlear and vestibular microcirculation to reduce endolymphatic hydrops.

Question 3

A vestibular therapist should educate patients taking benzodiazepines for vertigo that long-term use:

Accepted Answer

May slow or impair central vestibular compensation

Answer

Benzodiazepines suppress CNS activity, reducing the error signals that drive neuroplastic vestibular compensation and delaying recovery.

Question 4

Scopolamine transdermal patches are most commonly used in vestibular care to treat:

Accepted Answer

Motion sickness

Answer

Scopolamine, an anticholinergic, blocks muscarinic receptors in the vestibular nucleus and vomiting center, making it effective for motion sickness prevention.

Question 5

Which medication class used for vestibular migraine prophylaxis includes topiramate and valproate?

Accepted Answer

Anticonvulsants and mood stabilizers

Answer

Anticonvulsants such as topiramate and valproate reduce cortical spreading depression and neuronal hyperexcitability implicated in vestibular migraine.

(CVT) Certified Vestibular Therapist Practice Test

(CVT) Certified Vestibular Therapist Practice Test

CVT CVT Pharmacology & Medication Effects on Vestibular Function 2