A renal transplant recipient is found to have donor-specific antibodies (DSAs) against HLA-DQ7 at 18 months post-transplant with a stable creatinine. This finding is best described as:
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A
Subclinical antibody-mediated rejection requiring immediate plasma exchange
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B
De novo DSA, a risk factor for chronic allograft nephropathy warranting close surveillance
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C
A benign finding that requires no intervention
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D
Evidence of ABO incompatibility developing late post-transplant