CCTC Pre-Transplant Candidate Evaluation 2

Question 1

A 58-year-old patient with end-stage renal disease has a panel reactive antibody (PRA) of 85%. What does this indicate for transplant planning?

Accepted Answer

The patient is highly sensitized and will have difficulty finding a compatible donor

Answer

A PRA of 85% means the patient has antibodies against 85% of the donor pool, making compatible organ matching significantly more difficult.

Question 2

Which cardiac evaluation is typically required before listing a patient with diabetes mellitus for kidney transplantation?

Accepted Answer

Stress testing or coronary angiography to assess for occult coronary artery disease

Answer

Diabetic patients are at high risk for silent coronary artery disease, so functional stress testing or angiography is standard pre-listing cardiac evaluation.

Question 3

A transplant candidate is found to have a positive PPD skin test with no prior BCG vaccination and no active symptoms. What is the appropriate management?

Accepted Answer

Prophylactic isoniazid (INH) therapy before and after transplant

Answer

Latent TB identified by positive PPD without prior BCG warrants prophylactic INH to prevent reactivation after immunosuppression.

Question 4

During pre-transplant psychosocial evaluation, a candidate discloses ongoing alcohol use despite prior treatment. What is the transplant team's most appropriate next step?

Accepted Answer

Require a mandatory sobriety period and engagement with addiction treatment before listing

Answer

Most transplant programs require documented sobriety (typically 6 months) and active addiction treatment engagement before listing alcohol-dependent candidates.

Question 5

Which finding on abdominal imaging would most concern the transplant team when evaluating a liver transplant candidate?

Accepted Answer

Portal vein thrombosis extending into the superior mesenteric vein

Answer

Extensive portal vein thrombosis involving the superior mesenteric vein significantly complicates liver transplant surgery and may be a contraindication.

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC Pre-Transplant Candidate Evaluation 2