CCTC Organ Procurement and Preservation 4

Question 1

Which preservation solution is most commonly used for pancreas preservation due to its high viscosity and oncotic properties?

Accepted Answer

University of Wisconsin (UW) solution

Answer

UW solution contains hydroxyethyl starch which provides oncotic support and is the gold standard for pancreas preservation, allowing up to 30 hours of cold ischemia.

Question 2

During back-table preparation of a donor kidney, the transplant coordinator notices the renal artery has an accessory lower pole artery. What is the appropriate action?

Accepted Answer

Document and report the finding to the surgical team for reconstruction planning

Answer

Accessory renal arteries must be documented and communicated to the surgical team so they can plan appropriate reconstruction to ensure adequate blood supply to all segments of the kidney.

Question 3

What is the primary purpose of pulsatile machine perfusion (PMP) compared to static cold storage for kidneys?

Accepted Answer

It provides continuous flow that may reduce delayed graft function and allows viability assessment

Answer

Pulsatile machine perfusion maintains continuous flow mimicking physiologic conditions, which may reduce ischemia-reperfusion injury and allows real-time monitoring of renal resistance and flow as viability markers.

Question 4

A donor is declared brain dead and consent is obtained. Before organ procurement, the coordinator notes the donor's creatinine has risen from 0.9 to 2.8 mg/dL over 24 hours. What is the best course of action?

Accepted Answer

Notify the transplanting surgeon and OPO medical director to evaluate the clinical context

Answer

Rising creatinine in brain-dead donors is common due to hemodynamic instability and requires clinical context evaluation; the decision to accept or decline organs rests with the transplanting surgeon in collaboration with the OPO medical director.

Question 5

What is the maximum recommended cold ischemia time for a donor liver to minimize primary non-function risk?

Accepted Answer

12 hours

Answer

Liver cold ischemia time should ideally be kept under 12 hours, as times exceeding this threshold significantly increase the risk of primary non-function and ischemic cholangiopathy.

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC Organ Procurement and Preservation 4