CCTC Organ Procurement and Preservation 3

Question 1

Which organization maintains the national deceased donor organ allocation system in the United States?

Accepted Answer

United Network for Organ Sharing (UNOS)

Answer

UNOS operates the OPTN (Organ Procurement and Transplantation Network) under federal contract with HRSA and manages national organ allocation policies and waiting lists.

Question 2

The Kidney Donor Profile Index (KDPI) is primarily used to:

Accepted Answer

Estimate the relative risk of graft failure compared to an ideal kidney donor

Answer

KDPI is a numerical score (0–100%) derived from donor characteristics that estimates the relative risk of graft failure; a higher KDPI indicates a higher risk organ.

Question 3

Normothermic machine perfusion (NMP) differs from hypothermic machine perfusion (HMP) in that NMP:

Accepted Answer

Maintains the organ at physiologic temperature with oxygenated blood or perfusate

Answer

NMP keeps organs at approximately 37°C with oxygenated perfusate, allowing active cellular metabolism and superior viability assessment compared to cold HMP.

Question 4

In DCD donation, functional warm ischemia time (fWIT) begins when:

Accepted Answer

Systolic blood pressure falls below 50 mmHg or SpO2 falls below 70%

Answer

Functional warm ischemia time begins when hemodynamic instability renders organ perfusion inadequate (SBP <50 mmHg or SpO2 <70%), which may precede cardiac arrest.

Question 5

What is the primary goal of hemodynamic management in a brain-dead donor during the donation process?

Accepted Answer

Optimizing organ perfusion and viability for successful transplantation

Answer

After brain death is declared, clinical management shifts from donor survival to optimizing organ perfusion, oxygenation, and metabolic stability to maximize transplantable organ quality.

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC Organ Procurement and Preservation 3