CCTC Long-Term Recipient Management 2

Question 1

A kidney transplant recipient at 3 years post-transplant has a serum creatinine that has slowly risen from 1.2 to 2.1 mg/dL over 6 months. The most likely diagnosis is:

Accepted Answer

Chronic allograft nephropathy

Answer

Slowly progressive decline in renal function years after transplant is the hallmark of chronic allograft nephropathy (interstitial fibrosis/tubular atrophy).

Question 2

Which vaccine is CONTRAINDICATED in solid organ transplant recipients on immunosuppression?

Accepted Answer

Live attenuated varicella zoster vaccine

Answer

Live attenuated vaccines are contraindicated in immunocompromised transplant recipients due to risk of vaccine-strain infection.

Question 3

A liver transplant recipient develops hypertension, hyperlipidemia, and new-onset diabetes 2 years post-transplant. These findings together are best described as:

Accepted Answer

Post-transplant metabolic syndrome

Answer

The cluster of hypertension, dyslipidemia, and new-onset diabetes after transplant (NODAT) defines post-transplant metabolic syndrome, largely driven by immunosuppression.

Question 4

Which malignancy has the highest increased incidence in long-term transplant recipients compared to the general population?

Accepted Answer

Non-melanoma skin cancer

Answer

Non-melanoma skin cancers (squamous and basal cell) are dramatically more common in transplant recipients, with squamous cell carcinoma occurring up to 100 times more often.

Question 5

A transplant coordinator is counseling a 5-year post-kidney-transplant recipient about sun protection. The PRIMARY reason is:

Accepted Answer

Immunosuppression increases skin cancer risk

Answer

Chronic immunosuppression impairs immune surveillance against skin carcinogenesis, making sun protection critical for long-term recipients.

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC Long-Term Recipient Management 2