CCTC Evaluation and Preparation for Transplant 3

Question 1

A heart transplant candidate with a history of treated lymphoma is being evaluated. What minimum cancer-free interval is generally required before listing?

Accepted Answer

2 years

Answer

Most transplant centers require at least 2 to 5 years of cancer-free interval depending on tumor type and stage, balancing recurrence risk against transplant urgency.

Question 2

Which hepatic lesion scoring system is used to prioritize liver transplant candidates with hepatocellular carcinoma (HCC) within UNOS criteria?

Accepted Answer

Milan Criteria with MELD exception points

Answer

Candidates with HCC within Milan Criteria (1 lesion ≤5 cm or up to 3 lesions ≤3 cm each, no vascular invasion) receive MELD exception points to improve their allocation priority.

Question 3

When evaluating a patient for kidney-pancreas transplant, which condition in the recipient must be present to justify simultaneous pancreas transplantation?

Accepted Answer

Type 1 diabetes with end-stage renal disease

Answer

Simultaneous pancreas-kidney (SPK) transplant is primarily indicated in Type 1 diabetics with ESRD, as both organs address insulin deficiency and its renal complications.

Question 4

During psychosocial evaluation, which factor is considered an ABSOLUTE contraindication to transplant listing at most centers?

Accepted Answer

Active alcohol or substance abuse without documented sobriety

Answer

Active substance abuse without documented sobriety and treatment is an absolute contraindication because it predicts non-adherence and graft failure.

Question 5

A transplant coordinator reviews crossmatch results and notes a positive T-cell crossmatch. What does this finding indicate?

Accepted Answer

Presence of donor-specific antibodies against HLA class I antigens; transplant is contraindicated

Answer

A positive T-cell crossmatch indicates DSA against class I HLA on donor T-cells, predicting hyperacute or accelerated rejection and is a contraindication to transplant.

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC - Certified Clinical Transplant Coordinator Practice Test

CCTC Evaluation and Preparation for Transplant 3