AMC MCQ Musculoskeletal and Dermatology 2

Question 1

A 55-year-old man presents with sudden severe pain, redness and swelling of the first metatarsophalangeal joint. What is the most likely diagnosis?

Accepted Answer

Acute gout

Answer

Acute podagra of the first MTP joint with rapid onset is classic for gout.

Question 2

Which investigation is most useful to confirm a diagnosis of gout in a swollen joint?

Accepted Answer

Joint aspiration with polarised microscopy

Answer

Negatively birefringent needle-shaped urate crystals on aspirate confirm gout.

Question 3

A 30-year-old woman has symmetrical pain and stiffness of the small joints of both hands, worse in the morning for over an hour. What is the most likely diagnosis?

Accepted Answer

Rheumatoid arthritis

Answer

Symmetrical small-joint involvement with prolonged morning stiffness suggests rheumatoid arthritis.

Question 4

Which antibody is most specific for rheumatoid arthritis?

Accepted Answer

Anti-cyclic citrullinated peptide (anti-CCP)

Answer

Anti-CCP antibodies are highly specific for rheumatoid arthritis.

Question 5

A child presents with a salmon-pink, erythematous rash, high spiking fevers and arthritis. Which condition is most likely?

Accepted Answer

Systemic juvenile idiopathic arthritis

Answer

Spiking fevers with an evanescent salmon-pink rash and arthritis indicate systemic JIA (Still disease).

AMC MCQ Practice Test

AMC MCQ Practice Test

AMC MCQ Musculoskeletal and Dermatology 2