ALAT ALAT Species-Specific Care and Experimental Models Questions and Answers 5

Question 1

Ferrets are commonly used as an animal model for which human infectious disease because they share similar receptor distribution in the respiratory tract?

Accepted Answer

Influenza

Answer

Ferrets have sialic acid receptors in the respiratory tract similar to humans, making them an excellent model for influenza virus infection and transmission studies.

Question 2

Which of the following statements about Mongolian gerbils used as laboratory animals is correct?

Accepted Answer

They are prone to spontaneous epileptiform seizures

Answer

Approximately 20-40% of Mongolian gerbils develop spontaneous epileptiform seizures, making them a naturally occurring model for epilepsy research.

Question 3

A non-human primate (NHP) is observed self-mutilating and showing stereotypic behaviors. The most appropriate first response is to:

Accepted Answer

Notify the veterinary staff and implement environmental enrichment strategies

Answer

Self-mutilation and stereotypies in NHPs typically indicate psychological distress; the veterinary team should be notified and environmental enrichment implemented immediately.

Question 4

The Sprague-Dawley rat is most accurately described as:

Accepted Answer

An outbred stock commonly used in toxicology and pharmacology studies

Answer

Sprague-Dawley is an outbred stock of rat, characterized by genetic diversity, and is widely used in general biomedical, toxicology, and pharmacology research.

Question 5

Which of the following correctly describes why guinea pigs require dietary vitamin C supplementation?

Accepted Answer

Guinea pigs lack the enzyme L-gulonolactone oxidase needed to synthesize vitamin C

Answer

Guinea pigs, like humans and some primates, lack L-gulonolactone oxidase and therefore cannot synthesize vitamin C endogenously, requiring dietary supplementation.

ALAT - Assistant Laboratory Animal Technician Practice Test

ALAT - Assistant Laboratory Animal Technician Practice Test

ALAT ALAT Species-Specific Care and Experimental Models Questions and Answers 5