Urgent Care Urgent Care for Allergic Reactions and Anaphylaxis 1

Question 1

What is the first-line treatment for anaphylaxis in an urgent care setting?

Accepted Answer

Epinephrine 0.3mg IM (1:1000)

Answer

Epinephrine IM is the only first-line treatment for anaphylaxis; antihistamines and corticosteroids are adjuncts and must never replace it.

Question 2

At which anatomical site should epinephrine be injected for anaphylaxis in adults?

Accepted Answer

Anterolateral aspect of the mid-thigh

Answer

The anterolateral thigh provides faster absorption and higher peak plasma concentrations than other IM sites, making it the preferred injection location.

Question 3

Which combination of symptoms is classic for anaphylaxis?

Accepted Answer

Urticaria, angioedema, and bronchospasm

Answer

Anaphylaxis classically involves cutaneous (urticaria/angioedema), respiratory (bronchospasm), and/or cardiovascular manifestations occurring rapidly after allergen exposure.

Question 4

What is the minimum recommended observation period after treating anaphylaxis in urgent care?

Accepted Answer

4-6 hours

Answer

A minimum 4-6 hour observation period is recommended after anaphylaxis treatment to monitor for biphasic reactions, which can recur without re-exposure to the allergen.

Question 5

What is a biphasic anaphylactic reaction?

Accepted Answer

Recurrence of anaphylaxis symptoms after apparent resolution without re-exposure to allergen

Answer

Biphasic anaphylaxis is the recurrence of symptoms 1-72 hours after the initial reaction has resolved, without additional allergen exposure.

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Urgent Care Urgent Care for Allergic Reactions and Anaphylaxis 1