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TBI Pharmacological Management Flashcards

6 cards from real TBI practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 TBI Pharmacological Management flashcards as text

  1. Propranolol is sometimes used post-TBI primarily to treat which condition?

    Answer: Autonomic dysreflexia and sympathetic storming

    Sympathetic storming (paroxysmal sympathetic hyperactivity) after TBI is often managed with propranolol to blunt adrenergic surges.

  2. Which medication is avoided in TBI due to its potential to lower the seizure threshold?

    Answer: Tramadol

    Tramadol lowers the seizure threshold and is generally avoided in TBI patients who are already at elevated seizure risk.

  3. What is the role of methylphenidate in post-acute TBI rehabilitation?

    Answer: Improve attention, processing speed, and cognitive fatigue

    Methylphenidate (Ritalin) is used off-label in TBI rehab to improve attention, alertness, and cognitive processing speed.

  4. Hypertonic saline is used in TBI management primarily as an alternative to which drug?

    Answer: Mannitol

    Hypertonic saline serves as an osmotic therapy alternative to mannitol for reducing elevated intracranial pressure.

  5. Why is corticosteroid use (e.g., dexamethasone) contraindicated in acute TBI?

    Answer: The CRASH trial showed increased mortality with corticosteroids in TBI

    The landmark CRASH trial demonstrated that methylprednisolone infusion in acute TBI significantly increased 2-week mortality.

  6. Which medication is used to manage spasticity following TBI by acting as a GABA-B receptor agonist?

    Answer: Baclofen

    Baclofen acts on GABA-B receptors in the spinal cord to reduce muscle spasticity common after TBI.

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