QMA Insulin QMA Insulin Storage and Handling 1 — Questions and Answers
Question 1: At what temperature range should unopened insulin vials be stored to maintain potency?
- 36°F to 46°F (2°C to 8°C) in the refrigerator (Correct answer)
- Below 32°F (0°C) in the freezer
- 68°F to 77°F (20°C to 25°C) at room temperature
- Above 85°F (29°C) in a warm cabinet
Correct answer: 36°F to 46°F (2°C to 8°C) in the refrigerator
Unopened insulin vials should be stored in the refrigerator at 36°F to 46°F to maintain potency until the expiration date.
Question 2: How long can an opened insulin vial typically be kept at room temperature before it must be discarded?
- 28 days (Correct answer)
- 7 days
- 90 days
- 6 months
Correct answer: 28 days
Most opened insulin vials can be kept at room temperature (below 77°F/25°C) for up to 28 days, after which they should be discarded.
Question 3: What should a QMA do if insulin appears cloudy, discolored, or has visible particles (for a type that should be clear)?
- Discard the insulin and obtain a new vial (Correct answer)
- Shake the vial vigorously to dissolve particles
- Warm the vial under hot water
- Use the insulin but document the appearance
Correct answer: Discard the insulin and obtain a new vial
Insulin that appears abnormal — cloudy, discolored, or with particles when it should be clear — must be discarded as it may be contaminated or degraded.
Question 4: Why should insulin never be frozen?
- Freezing destroys the protein structure, making it ineffective (Correct answer)
- Freezing causes insulin to become too concentrated
- Freezing makes insulin unsafe to inject due to ice crystals
- Freezing changes the color of insulin permanently
Correct answer: Freezing destroys the protein structure, making it ineffective
Freezing damages the protein structure of insulin, rendering it ineffective and potentially harmful if administered.
Question 5: When rolling (not shaking) an insulin vial before use, what type of insulin requires this step?
- NPH (intermediate-acting cloudy insulin) (Correct answer)
- Regular (short-acting clear insulin)
- Glargine (long-acting clear insulin)
- Aspart (rapid-acting clear insulin)
Correct answer: NPH (intermediate-acting cloudy insulin)
NPH insulin is a suspension that settles and must be gently rolled between the palms to re-suspend the particles before drawing the dose.
Question 6: What is the correct action when an insulin pen is exposed to temperatures above 77°F (25°C) for an extended period?
- Discard the pen and use a new one (Correct answer)
- Place it in the freezer immediately to restore potency
- Shake the pen to re-activate the insulin
- Continue to use it but administer a larger dose
Correct answer: Discard the pen and use a new one
Insulin exposed to excessive heat for prolonged periods loses potency and should be discarded to ensure accurate dosing.
At what temperature range should unopened insulin vials be stored to maintain potency?