PTCB Pharmacology #4 2

Question 1

Which of the following drugs is a direct thrombin inhibitor?

Accepted Answer

Dabigatran

Answer

Apixaban

Answer

Clopidogrel

Answer

Fondaparinux

Question 2

What is the antidote for acetaminophen overdose?

Accepted Answer

N-acetylcysteine

Answer

Flumazenil

Answer

Naloxone

Answer

Protamine sulfate

Question 3

Which drug class do "-floxacin" suffix drugs belong to?

Accepted Answer

Fluoroquinolones

Answer

Cephalosporins

Answer

Aminoglycosides

Answer

Macrolides

Question 4

Diphenhydramine (Benadryl) is associated with which class of adverse effects in elderly patients?

Accepted Answer

Anticholinergic effects (confusion, urinary retention, constipation)

Answer

Nephrotoxicity

Answer

Hepatotoxicity

Answer

Ototoxicity

Question 5

Which of the following is the correct mechanism of metformin?

Accepted Answer

Activates AMPK, reducing hepatic glucose production and improving insulin sensitivity

Answer

Stimulates insulin secretion from pancreatic beta cells

Answer

Inhibits glucose absorption in the intestine

Answer

Increases urinary glucose excretion

Question 6

Which of the following is a side effect unique to ARBs but NOT ACE inhibitors?

Accepted Answer

Dry cough is absent (ARBs do not cause cough)

Answer

Hyperkalemia

Answer

Hypotension

Answer

Renal impairment