Pharmacy Compounding 5

Question 1

Which emulsifying agent is an example of a cationic surfactant used in compounding?

Accepted Answer

Benzalkonium chloride

Answer

Sodium lauryl sulfate

Answer

Polysorbate 80 (Tween 80)

Answer

Lecithin

Question 2

A compounded preparation is described as a 'W/O emulsion.' This means:

Accepted Answer

Water is the dispersed phase and oil is the continuous phase

Answer

Oil is the dispersed phase and water is the continuous phase

Answer

Water and oil are mixed without an emulsifier

Answer

Water is supersaturated with an oil-soluble drug

Question 3

Which pH range is generally considered most appropriate for a compounded ophthalmic preparation to minimize irritation?

Accepted Answer

6.5–7.5

Answer

3.0–5.0

Answer

5.0–6.5

Answer

8.0–9.5

Question 4

A 503B outsourcing facility differs from a 503A compounding pharmacy primarily because 503B facilities:

Accepted Answer

May compound without patient-specific prescriptions in larger quantities for office stock

Answer

Only compound for veterinary use

Answer

Are exempt from all FDA inspections

Answer

Cannot compound sterile preparations

Question 5

When compounding a transdermal gel using PLO (Pluronic Lecithin Organogel), the lecithin component serves primarily as:

Accepted Answer

A penetration enhancer that increases skin permeation

Answer

A preservative

Answer

A thickening agent

Answer

An antioxidant

Question 6

Which type of balance is required when weighing quantities less than 120 mg in a pharmacy compounding setting?

Accepted Answer

Electronic analytical balance

Answer

Class A prescription balance

Answer

Torsion balance

Answer

Triple beam balance

Question 7

Stability testing during compounding quality assurance most commonly evaluates which parameters? (Select the best answer)

Accepted Answer

Color, odor, pH, and drug concentration over time

Answer

Only the appearance and smell

Answer

Sterility and endotoxin levels only

Answer

Container closure integrity only